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Merck
CN

435007

Hydroxypropyl cellulose

average Mw ~80,000, powder, 20 mesh particle size (99% through)

Synonym(s):

HPC, Cellulose & cellulose derivatives

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About This Item

CAS Number:
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
Technical Service
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description

biological oxygen demand (BOD) 14,000 ppm

Quality Segment

form

powder

autoignition temp.

752 °F

mol wt

average Mw ~80,000

impurities

<5 wt. %

particle size

20 mesh (99% through)

pH

5.0-8.5

interfacial tension mineral oil

12.5 dyn/cm, 0.1 wt. % in H2O (vs. mineral oil)

viscosity

250-800 cP, 10 wt. % in H2O(25 °C)(lit.)

solubility

H2O: insoluble (above 45 °C), polar organic solvents: soluble

density

0.5 g/mL at 25 °C (lit.)

SMILES string

N(C)(C)c1cc(c(cc1)C(N)CC)C

InChI

1S/C12H20N2/c1-5-12(13)11-7-6-10(14(3)4)8-9(11)2/h6-8,12H,5,13H2,1-4H3

InChI key

RRHXDYJWVYFMKV-UHFFFAOYSA-N

General description

Hydroxypropyl cellulose (HPC) is biocompatible in nature and exhibits low critical solution temperature (LCST). It has been reported to be prepared by reacting cellulose with alkali, producing alkali cellulose which is consecutively reacted with propylene oxide. HPC is soluble in water at lower than RT. Viscosity behaves inversely to rise in temperature.

Application

Copolymers composed of HPC backbones with poly((2-dimethyl amino)ethyl methacrylate side chains has been synthesized for gene delivery. HPC has been used as a binder in to nanostructured anatase membranes. Polymer conjugates made of HPC backbones and poly(N-isopropylacryamide) as side chains act as smart hydrogels. HPC has been reported to be studied as a glue.


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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