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Merck
CN

435015

Methyl 2-hydroxyethyl cellulose

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About This Item

CAS Number:
9032-42-2
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
MFCD00147597

Key Documents

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SMILES string

O3[C@H]([C@@H]([C@H]([C@@H]([C@H]3COC)OC)OC)OC)O[C@@H]4[C@H](O[C@H]([C@@H]([C@H]4OC)OC)OC)COC.O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2O)O)O)CO.OCCO

InChI key

JTWZVKMWOCBJEV-RXUSYSPUSA-N

extent of labeling

0.06-0.50 mol hydroxyethyl per mol cellulose (M.S.)
8 wt. % hydroxyethyl
26 wt. % methoxy
1.3-2.2 mol methyl per mol cellulose (D.S.)

surface tension

45-55 dyn/cm, 20 °C, 0.1 wt. %

viscosity

15,000-20,500 cP, 2 wt. % in H2O(20 °C, Brookfield, spindle #6) (20 rpm)(lit.)

transition temp

flocculation range 60-90 °C (0.5 wt. %)

Quality Level

100

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Related Categories

Application

Water retention aid, thickening agent, protective colloid, suspending agent, binder and stabilizer.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCR5557
MKCS4685
MKCM4110
MKCK2600
MKBX7592V

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Rondedrick Sinville et al.
Electrophoresis, 29(23), 4751-4760 (2008-12-05)
We have developed a new method for the analysis of low abundant point mutations in genomic DNA using a combination of an allele-specific ligase detection reaction (LDR) with free-solution conjugate electrophoresis (FSCE) to generate and analyze the genetic products. FSCE
Su Jeong Ban et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(5), 1716-1721 (2012-03-06)
The effect of hydroxyethyl methylcellulose (HEMC) with different viscosities on the glucose metabolism and antioxidative defense system in high fat-fed mice was investigated. The mice were randomly divided into five dietary groups: normal control diet (NC), high fat diet (HF)
Roland Adden et al.
Analytical chemistry, 78(4), 1146-1157 (2006-02-16)
Hydroxyethylmethyl celluloses (HEMC, DS(Me) 1.46-1.66, DS(HE) = 0.14-0.17) have been analyzed with respect to their methyl and hydroxyethyl pattern in the glucosyl units and along the polymer chain. Methyl groups were located by GLC/MS after direct hydrolysis, reduction, and acetylation
S Zuleger et al.
International journal of pharmaceutics, 217(1-2), 139-152 (2001-04-09)
The present study deals with controlled drug delivery from hydrocolloid tablets by polymer particle erosion. The influence of excipients and formulation factors on the dissolution behaviour of the methyl hydroxyethyl cellulose (MHEC)-tablets is investigated. Linear drug release with low susceptibility
Su Jeong Ban et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(2), 130-134 (2011-11-01)
The effect of hydroxyethyl methylcellulose (HEMC), in comparison with hydroxypropyl methylcellulose (HPMC), on the body weight and lipid metabolism in mice fed with high fat diet was investigated. The animals were given normal control diet (NC group), high fat diet
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