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437018

N-Boc-1,6-hexanediamine hydrochloride

97%

Synonym(s):

N-Boc-1,6-diamino-hexane hydrochloride, tert-Butyl N-(6-aminohexyl)carbamate hydrochloride

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About This Item

Linear Formula:
(CH3)3COCONH(CH2)6NH2 · HCl
CAS Number:
65915-94-8
Molecular Weight:
252.78
UNSPSC Code:
12352116
NACRES:
NA.22
PubChem Substance ID:
24867340
EC Number:
265-976-4
Beilstein/REAXYS Number:
3631740
MDL number:
MFCD00039072
eCl@ss:
32150312
Assay:
97%
Form:
solid
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Quality Segment

assay

97%

form

solid

reaction suitability

reagent type: cross-linking reagent

mp

162-164 °C (lit.)

functional group

Boc, amine

SMILES string

NCCCCCCNC(OC(C)(C)C)=O.[H]Cl

InChI

1S/C11H24N2O2.ClH/c1-11(2,3)15-10(14)13-9-7-5-4-6-8-12;/h4-9,12H2,1-3H3,(H,13,14);1H

InChI key

JSBWQIZQJOQPFN-UHFFFAOYSA-N

Application

N-Boc-1,6-hexanediamine hydrochloride is a general reagent to introduce a C6-spacer. It can be used in:
  • Synthesis of poly(L-glutamic acid) gadolinium chelates as biodegradable MRI contrast agents.
  • Synthesis of cholesteryl-functionalized hyaluronic acid-based anionic nanogel for protein delivery.
  • Preparation of amphiphilic prodrug, containing anticancer drug chlorambucil, which would self-assemble to form micelles in aqueous solution.

Reagent for the introduction of a C6-spacer.

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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