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Merck
CN

440183

(3-Chloropropyl)trimethoxysilane

≥97%

Synonym(s):

δ-Chloropropyltrimethoxysilane, (γ-Chloropropyl)trimethoxysilane, (3-Chloropropyl)trimethoxysilane, 3-(Trimethoxysilyl)propyl chloride

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About This Item

Linear Formula:
Cl(CH2)3Si(OCH3)3
CAS Number:
2530-87-2
Molecular Weight:
198.72
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
24867575
EC Number:
219-787-9
Beilstein/REAXYS Number:
969627
MDL number:
MFCD00000997

Key Documents

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Product Name

(3-Chloropropyl)trimethoxysilane, ≥97%

InChI key

OXYZDRAJMHGSMW-UHFFFAOYSA-N

InChI

1S/C6H15ClO3Si/c1-8-11(9-2,10-3)6-4-5-7/h4-6H2,1-3H3

SMILES string

CO[Si](CCCCl)(OC)OC

assay

≥97%

form

liquid

refractive index

n20/D 1.419 (lit.)

bp

195 °C/750 mmHg (lit.)

density

1.09 g/mL at 25 °C (lit.)

Quality Level

100

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Application

(3-Chloropropyl)trimethoxysilane may be used in the synthesis of octakis(3-chloropropyl)octasilsesquioxane.{35}
CPTMS can be used to silanize a variety of nanoparticles like carbon nanotubes (CNT) and silica nanoparticles (SiO2) for different applications like development for molecularly imprinted polymers for protein detection and fabrication of mesoporous silica(organic-inorganic hybrid). It may be used to functionalize silica-iron oxide nanoparticles which can be used as catalysts for the synthesis of pyrano(3,2−c:5,6−c′)dichromene-6,8-dione derivatives.

General description

(3-Chloropropyl)trimethoxysilane (CPTMS) is an organo-silane which forms a self-assembled monolayer (SAMs) that facilitates the surface modification of different bio-and nano- materials.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

161.1 °F - closed cup

flash_point_c

71.7 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW3956
MKCQ3899
SHBK5638
SHBJ9862
SHBG0007V

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Marie-Alexandra Neouze et al.
Monatshefte fur chemie, 143(4), 519-525 (2012-01-01)
A newly arising challenge in the field of nanoparticle research concerns the control and the understanding of the interparticle interactions and interparticle properties. This should allow the development of materials based on nanoparticle assemblies which represents a great opportunity to
Feng Wang et al.
Frontiers in bioengineering and biotechnology, 8, 589-589 (2020-07-28)
The juice clarification, one of the key steps in juice processing, suffers from haze formation that results from residual phenolic compounds. In this study, laccase was immobilized on metal-chelated magnetic silica nanoparticles and used for continuous juice clarification in a
M C Neves et al.
Materials today. Bio, 8, 100086-100086 (2020-12-16)
Nucleic acids are relevant biopolymers in therapy and diagnosis, for which their purity and biological activity are of crucial relevance. However, these features are difficult to achieve by cost-effective methods. Herein, we report the functionalization of a macroporous chromatographic support
Relation between the wetting effect and the adsorbed amount of water-soluble polymers or proteins at various interfaces.
Pandey LM and Pattanayek SK
Journal of Chemical and Engineering Data, 58(12), 3440-3446 (2013)
One-pot synthesis and modification of silica nanoparticles with 3-chloropropyl-trimethoxysilane assisted by microwave irradiation.
De Conto JF, et al.
Chemical Engineering Communications , 205(4), 533-537 (2018)
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