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440736

4-Thiouracil

97%

Synonym(s):

2-Hydroxy-4-mercaptopyrimidine

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About This Item

Empirical Formula (Hill Notation):
C4H4N2OS
CAS Number:
591-28-6
Molecular Weight:
128.15
NACRES:
NA.22
PubChem Substance ID:
24867621
UNSPSC Code:
12352100
MDL number:
MFCD00090842
Assay:
97%
Form:
powder
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Quality Level

200

assay

97%

form

powder

mp

295 °C (dec.) (lit.)

solubility

1 M NaOH: soluble 50 mg/mL

SMILES string

Oc1nccc(S)n1

InChI

1S/C4H4N2OS/c7-4-5-2-1-3(8)6-4/h1-2H,(H2,5,6,7,8)

InChI key

OVONXEQGWXGFJD-UHFFFAOYSA-N

Application

4-Thiouracil is suitable reagent employed in Schneider′s media for the embryos during RNA extraction. It may be employed as reagent for the Northwestern blotting technique.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN2344
BCCK9983
BCCM0548
BCCG6375
BCCF2648

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Jeanine S Morey et al.
PloS one, 8(6), e66347-e66347 (2013-06-19)
Dinoflagellates possess many physiological processes that appear to be under post-transcriptional control. However, the extent to which their genes are regulated post-transcriptionally remains unresolved. To gain insight into the roles of differential mRNA stability and de novo transcription in dinoflagellates
Structure and tautomerism of the neutral and monoanionic forms of 4-thiouracil derivatives.
A Psoda et al.
Journal of the American Chemical Society, 96(22), 6832-6839 (1974-10-30)
Linda Warfield et al.
Molecular cell, 68(1), 118-129 (2017-09-19)
Previous studies suggested that expression of most yeast mRNAs is dominated by either transcription factor TFIID or SAGA. We re-examined the role of TFIID by rapid depletion of S. cerevisiae TFIID subunits and measurement of changes in nascent transcription. We find that
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Global Trade Item Number

SKUGTIN
440736-1G04061832253374