445495
Maleamic acid
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About This Item
Linear Formula:
H2NCOCH=CHCO2H
CAS Number:
Molecular Weight:
115.09
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
form
solid
mp
158-161 °C (lit.)
functional group
amide
carboxylic acid
SMILES string
[H]\C(=C(/[H])C(O)=O)C(N)=O
InChI
1S/C4H5NO3/c5-3(6)1-2-4(7)8/h1-2H,(H2,5,6)(H,7,8)/b2-1-
InChI key
FSQQTNAZHBEJLS-UPHRSURJSA-N
Related Categories
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Maleamic and citraconamic acids, methyl esters, and imides.
MEHTA NB, et al.
The Journal of Organic Chemistry, 25(6), 1012-1015 (1960)
Meifang Huang et al.
International journal of biological macromolecules, 36(1-2), 98-102 (2005-06-14)
N-maleamic acid-chitosan was synthesized and characterized by Fourier transform infrared spectra analysis (FT-IR) and 1H NMR. The graft copolymerization of N-maleamic acid-chitosan and butyl acrylate (BA) in acetic acid aqueous solution was investigated, using the gamma-ray of 60Co gamma-irradiation method.
Juan Rodrigues et al.
Pharmaceutical research, 28(4), 907-919 (2010-12-25)
The objective of this study was to investigate the effect of new 4-maleamic acid and 4-maleamide peptidyl chalcone derivatives against human prostate cancer in vitro and in vivo. From a series of 21 chalcones, the effects of the three best
Virginia A Kincaid et al.
Biochemistry, 51(1), 545-554 (2012-01-05)
The penultimate reaction in the oxidative degradation of nicotinate (vitamin B(3)) to fumarate in several species of aerobic bacteria is the hydrolytic deamination of maleamate to maleate, catalyzed by maleamate amidohydrolase (NicF). Although it has been considered a model system
José I Jiménez et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(32), 11329-11334 (2008-08-06)
The aerobic catabolism of nicotinic acid (NA) is considered a model system for degradation of N-heterocyclic aromatic compounds, some of which are major environmental pollutants; however, the complete set of genes as well as the structural-functional relationships of most of
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