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Merck
CN

45150

Sigma-Aldrich

Pamoic acid

≥97.0% (T)

Synonym(s):

1,1′-Methylene-bis(2-hydroxy-3-naphthoic acid), 4,4′-Methylenebis(3-hydroxy-2-naphthoic acid), Embonic acid

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About This Item

Empirical Formula (Hill Notation):
C23H16O6
CAS Number:
130-85-8
Molecular Weight:
388.37
Beilstein:
901319
EC Number:
204-998-0
MDL number:
MFCD00004079
UNSPSC Code:
12352100
PubChem Substance ID:
57650260
NACRES:
NA.22

Key Documents

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Quality Level

100

Assay

≥97.0% (T)

mp

≥300 °C (dec.)

functional group

carboxylic acid

SMILES string

OC(=O)c1cc2ccccc2c(Cc3c(O)c(cc4ccccc34)C(O)=O)c1O

InChI

1S/C23H16O6/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29/h1-10,24-25H,11H2,(H,26,27)(H,28,29)

InChI key

WLJNZVDCPSBLRP-UHFFFAOYSA-N

Gene Information

human ... PTPN1(5770), PTPRF(5792)

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Related Categories

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF4818V
WXBF2970V
BCCJ6931
BCCF1034
BCCD9240

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Multi-component hydrogen-bonding assembly of a pharmaceutical agent pamoic acid with piperazine or 4, 4'-bipyridyl: A channel hydrated salt with multiple-helical motifs vs a bimolecular cocrystal.
Du M, et al.
Crystal Growth & Design, 9(4), 1655-1657 (2009)
Pamoic acid determined from powder diffraction data.
Haynes DA, et al.
Acta Crystallographica Section E, Structure Reports Online, 62(3), o1170-o1172 (2006)
A series of four-connected entangled metal-organic frameworks assembled from pamoic acid and pyridine-containing ligands: interpenetrating, self-penetrating, and supramolecular isomerism.
MLA Wang S, et al.
Crystal Growth & Design, 12(1), 79-92 (2011)
Chad Deisenroth et al.
Molecular and cellular biology, 30(16), 3981-3993 (2010-06-16)
The ever-expanding knowledge of the role of p53 in cellular metabolism, apoptosis, and cell cycle control has led to increasing interest in defining the stress response pathways that regulate Mdm2. In an effort to identify novel Mdm2 binding partners, we
Ju-Yi Hsieh et al.
Oncotarget, 6(24), 20084-20098 (2015-05-27)
Here, we found a natural compound, embonic acid (EA), that can specifically inhibit the enzymatic activity of mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME, ME2) either in vitro or in vivo. The in vitro IC50 value of EA for m-NAD(P)-ME was 1.4
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