464139
6-Methoxysalicylic acid
98%
Synonym(s):
2-Hydroxy-6-methoxybenzoic acid
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About This Item
Linear Formula:
CH3OC6H3(OH)CO2H
CAS Number:
Molecular Weight:
168.15
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
98%
Form:
solid
Product Name
6-Methoxysalicylic acid, 98%
InChI
1S/C8H8O4/c1-12-6-4-2-3-5(9)7(6)8(10)11/h2-4,9H,1H3,(H,10,11)
SMILES string
COc1cccc(O)c1C(O)=O
InChI key
AAUQLHHARJUJEH-UHFFFAOYSA-N
assay
98%
form
solid
mp
134-138 °C (lit.)
functional group
carboxylic acid
Application
6-Methoxysalicylic acid has been used to fabricate a dummy template molecule required for the preparation of dummy molecularly imprinted polymers (DMIPs). These polymers are useful for the simultaneous selective removal and enrichment of ginkgolic acids (GAs) during the processing of Ginkgo biloba leaves. It may be employed as internal standard for the determination of acetylsalicylic acid (aspirin, ASA) and its major metabolite, salicylic acid (SA), in animal plasma by LC/MS/MS.
General description
6-Methoxysalicylic acid has been reported to exhibit significant analgesic effects.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Francisco Palacios-Espinosa et al.
Journal of ethnopharmacology, 118(3), 448-454 (2008-06-28)
Brickellia veronicifolia (Kunth) Gray (Asteraceae) (BV) is broadly commercialized for treating gastrointestinal diseases (stomach aches, biliary colics and dyspepsia), arthritis, diabetes and painful inflammatory complaints. In order to complete the preclinical pharmacological profile of BV, first the antinociceptive effect of
Xiangrong Xu et al.
Biomedical chromatography : BMC, 23(9), 973-979 (2009-04-10)
A simple and sensitive analytical method using liquid chromatography-tandem mass spectrometry (LC/MS/MS) for determination of acetylsalicylic acid (aspirin, ASA) and its major metabolite, salicylic acid (SA), in animal plasma has been developed and validated. Both ASA and SA in plasma
Ecem Evrim Çelik et al.
Food research international (Ottawa, Ont.), 108, 286-294 (2018-05-08)
The interactions of coffee and bread crust melanoidins with hydroxycinnamic and hydroxybenzoic acids (HCA/HBA) containing different numbers of -OH and -OCH₃ groups localized at different positions on the aromatic ring were investigated. By doing so, mechanism of the interactions was
Wenhua Ji et al.
Journal of chromatography. A, 1368, 44-51 (2014-12-03)
Dummy molecularly imprinted polymers (DMIPs) for simultaneously selective removal and enrichment of ginkgolic acids (GAs) during the processing of Ginkgo biloba leaves have been prepared. Two dummy template molecule with similar structural skeleton to GAs, 6-methoxysalicylic acid (MOSA, DT-1) and
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