46746
Polyglycolic acid
Synonym(s):
PGA, Poly(2-hydroxyacetic acid)
InChI
1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
InChI key
AEMRFAOFKBGASW-UHFFFAOYSA-N
description
inherent viscosity 1.2 dl/g
Application
medical device
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Huaping Chen et al.
Biomaterials, 34(16), 4159-4172 (2013-03-14)
The absence of safe, efficient, cost-effective, and easily scalable delivery platforms is one of the most significant hurdles and critical issues that limit the bench to bedside translation of oligonucleotides-based therapeutics. Acid-labile materials are of special interest in developing nonviral
M A Tiunin et al.
Eksperimental'naia i klinicheskaia farmakologiia, 76(1), 3-6 (2013-03-07)
Technological parameters for the effective encapsulation of n-(1-phenethyl-4-piperidyl)propionanilide in poly(lactid-co-glycolide) (PLG) nanoparticles have been determined. Depending on the ratio of drug fractions adsorbed on the particle surface and associated with the polymer matrix, n-(1-phenethyl-4-piperidyl)propionanilide (200 microg/kg, i/m) loaded PLG nanospheres
Kevin S Tang et al.
Nanotechnology, 24(12), 125101-125101 (2013-03-06)
Magnetic PLGA nanoparticles are a significant advancement in the quest to translate MRI-based cell tracking to the clinic. The benefits of these types of particles are that they encapsulate large amounts of iron oxide nanocrystals within an FDA-approved polymer matrix
Toyin A Knight et al.
Methods in molecular biology (Clifton, N.J.), 1001, 179-188 (2013-03-16)
A tissue-engineered product needs to be properly characterized in order to be used in vivo. Many methods can be used to characterize a scaffold during creation of a tissue-engineered product. This chapter looks at the mechanical (tensile testing) and biological
A M Ribeiro et al.
Journal of biomedical nanotechnology, 9(2), 221-230 (2013-05-01)
Vaccines play an essential role in keeping humans healthy. Innovative approaches to their use include the utilization of plasmid DNA encoding sequences to express foreign antigens. DNAhsp65 from Mycobacterium leprae is suitable for this purpose due to its ability to
Articles
Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.
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