469157
6-Hydroxy-2-naphthoic acid
98%
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About This Item
Linear Formula:
HOC10H6CO2H
CAS Number:
Molecular Weight:
188.18
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
240-759-7
Beilstein/REAXYS Number:
2692084
MDL number:
Product Name
6-Hydroxy-2-naphthoic acid, 98%
InChI key
KAUQJMHLAFIZDU-UHFFFAOYSA-N
InChI
1S/C11H8O3/c12-10-4-3-7-5-9(11(13)14)2-1-8(7)6-10/h1-6,12H,(H,13,14)
SMILES string
OC(=O)c1ccc2cc(O)ccc2c1
assay
98%
mp
240-250 °C (lit.)
Quality Level
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Application
6-Hydroxy-2-naphthoic acid may be used in the synthesis of 5-bromo-6-hydroxy-2-naphthoic acid and liquid-crystalline epoxy resins.
General description
6-Hydroxy-2-naphthoic acid is a hydroxynaphthoic acid derivative. Whole cells of the recombinant Escherichia coli strain expressing CYP199A2 were reported to catalyze the regioselective oxidation of 6-hydroxy-2-naphthoic acid to afford 6,7-dihydroxynaphthoic acid. It can form co-crystals with caffeine.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Dejan-Kresimir Bucar et al.
Molecular pharmaceutics, 4(3), 339-346 (2007-05-11)
A group of caffeine-containing co-crystals of hydroxy-2-naphthoic acids were synthesized and analyzed via single-crystal X-ray diffraction and IR analysis. The imidazole-carboxylic acid synthon was observed in co-crystals involving 1-hydroxy-2-naphthoic and 3-hydroxy-2-naphthoic acid. In the case of 6-hydroxy-2-naphthoic acid, the co-crystal
Synthesis and characterization of wholly aromatic polyesters derived from 6-hydroxy-5-phenyl-2-naphthoic acid or 4'-hydroxy-3'-phenylbiphenyl-4-carboxylic acid and 4-hydroxybenzoic acid.
Huh S-M and Jin J.
Macromolecules, 30(10), 3005-3013 (1997)
New cholesteric liquid-crystal epoxy resins derived from 6-hydroxy-2-naphthoic acid.
Espinosa MA, et al.
Journal of Polymer Science Part A: Polymer Chemistry, 39(16), 2847-2858 (2001)
Mayumi Maeda et al.
Journal of bioscience and bioengineering, 126(2), 162-168 (2018-03-10)
Awamori is a traditional distilled liquor in the Ryukyu Islands, made from steamed rice by the action of the black-koji mold Aspergillus luchuensis and awamori yeast Saccharomyces cerevisiae. One of the specific flavors in aged awamori kusu is vanillin, which
Toshiki Furuya et al.
Bioscience, biotechnology, and biochemistry, 73(12), 2796-2799 (2009-12-08)
CYP199A2, a bacterial P450 monooxygenase from Rhodopseudomonas palustris, was found to exhibit oxidation activity towards three hydroxynaphthoic acids. Whole cells of the recombinant Escherichia coli strain expressing CYP199A2 efficiently catalyzed the regioselective oxidation of 1-, 3-, and 6-hydroxy-2-naphthoic acids to
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