471526
1-Dimethylamino-2-propanol
≥99%
Synonym(s):
N,N-Dimethylisopropanolamine
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About This Item
Linear Formula:
CH3CH(OH)CH2N(CH3)2
CAS Number:
Molecular Weight:
103.16
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
203-556-4
Beilstein/REAXYS Number:
1209244
MDL number:
Assay:
≥99%
vapor density
3.6 (vs air)
vapor pressure
8 mmHg ( 20 °C)
assay
≥99%
refractive index
n20/D 1.419 (lit.)
bp
121-127 °C (lit.)
density
0.837 g/mL at 25 °C (lit.)
SMILES string
CC(O)CN(C)C
InChI
1S/C5H13NO/c1-5(7)4-6(2)3/h5,7H,4H2,1-3H3
InChI key
NCXUNZWLEYGQAH-UHFFFAOYSA-N
General description
1-Dimethylamino-2-propanol (1DMA2P, DMAPH), a tertiary amine, is a dimethylamino-alcohol having high boiling point. It is a potent protector against mechlorethamine cytotoxicity and inhibitor of choline uptake. Kinetics of homogeneous reaction of carbon dioxide (CO2) with 1-dimethylamino-2-propanol in water has been investigated using stopped-flow technique.
Application
1-Dimethylamino-2-propanol solution may be used in the synthesis of the following:
- novel unsymmetrical 2,3,9,10,16,17,23-heptakis(alkoxyl)-24-mono(dimethylaminoalkoxyl)phthalocyanine compounds
- homoleptic nickel(II) aminoalkoxide
- Adduct with cobalt(II) 2,4-pentanedionate (acac)
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B
Storage Class
3 - Flammable liquids
wgk
WGK 1
flash_point_f
78.8 °F - DIN 51755 Part 1
flash_point_c
26 °C - DIN 51755 Part 1
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Regulatory Information
危险化学品
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S A Naujokaitis et al.
Journal of pharmaceutical sciences, 73(1), 34-39 (1984-01-01)
The structure-activity relationships of 2-dimethylaminoethanol and its analogues as protectors against mechlorethamine cytotoxicity and as inhibitors of choline uptake were evaluated. Of a series of inhibitors and protectors, 2-dimethylaminoethanol was the most potent inhibitor of choline uptake and the most
Synthesis and molecular structures of cobalt (II) ?-diketonate complexes as new MOCVD precursors for cobalt oxide films.
Pasko S, et al.
Polyhedron, 23(5), 735-741 (2004)
Soluble Ni II alkoxides based on dimethylaminoisopropoxide ligands: molecular structure of [Li (Pr i OH) Ni (η 2-OR)2 Cl]2 and of cis-NiCl2 (ROH)2 (R= CHMeCH2NMe2).
Hubert-Pfalzgraf LG, et al.
Polyhedron, 16(24), 4197-4203 (1997)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 471526-250ML | 04061832360133 |