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Merck
CN

475343

Thioglycolic acid

≥97%

Synonym(s):

Mercaptoacetic acid

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About This Item

Linear Formula:
HSCH2COOH
CAS Number:
Molecular Weight:
92.12
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-677-4
Beilstein/REAXYS Number:
506166
MDL number:
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InChI key

CWERGRDVMFNCDR-UHFFFAOYSA-N

InChI

1S/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4)

SMILES string

OC(=O)CS

vapor density

3.2 (vs air)

vapor pressure

0.4 mmHg ( 25 °C)

assay

≥97%

autoignition temp.

662 °F

Quality Level

bp

96 °C/5 mmHg (lit.)

mp

−16 °C (lit.)

density

1.326 g/mL at 20 °C (lit.)

storage temp.

2-8°C

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Legal Information

Product of Arkema Inc.

pictograms

Skull and crossbonesCorrosion

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

266.0 °F - closed cup

flash_point_c

130 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

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Fabian Hintzen et al.
International journal of pharmaceutics, 436(1-2), 120-126 (2012-06-12)
The aim of this study was to investigate the influence of molar mass of thiolated polymers (thiomers) on their in situ gelling properties. Chitosan-thioglycolic acid (chitosan-TGA) and pectin-cysteine (pectin-Cys) of increasing molar mass were chosen to produce in situ gels
Baofu Han et al.
Colloids and surfaces. B, Biointerfaces, 100, 209-214 (2012-07-07)
Fluorescent carbon dots (CDs) were solvothermaly synthesized in water-glycol medium by using glucose as carbon source and then modified with polyethyleneimine (PEI) for the first time to improve fluorescence quality. The as-prepared CDs were monodispersed sphere particles with a diameter
K Gradauer et al.
Journal of controlled release : official journal of the Controlled Release Society, 165(3), 207-215 (2012-12-12)
An ideal oral drug carrier should facilitate drug delivery to the gastrointestinal tract and its absorption into the systemic circulation. To meet these requirements, we developed a thiomer-coated liposomal delivery system composed of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and a maleimide-functionalized lipid, to
Takashi Kohno et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(4), 805-813 (2013-01-26)
Vascular smooth muscle cell (VSMC) migration is critically important for neointimal formation after vascular injury and atherosclerosis lesion formation. Copper (Cu) chelator inhibits neointimal formation, and we previously demonstrated that Cu transport protein antioxidant-1 (Atox1) is involved in Cu-induced cell
Gizem Ayna et al.
PloS one, 7(6), e40069-e40069 (2012-07-07)
Pathogen-activated and damage-associated molecular patterns activate the inflammasome in macrophages. We report that mouse macrophages release IL-1β while co-incubated with pro-B (Ba/F3) cells dying, as a result of IL-3 withdrawal, by apoptosis with autophagy, but not when they are co-incubated

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