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Merck
CN

47718

(Formylmethyl)triphenylphosphonium chloride

≥97.0% (AT)

Synonym(s):

2-Oxoethyltriphenylphosphonium chloride

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About This Item

Linear Formula:
HCOCH2P(Cl)(C6H5)3
CAS Number:
Molecular Weight:
340.78
UNSPSC Code:
12352114
NACRES:
NA.22
PubChem Substance ID:
EC Number:
263-767-2
Beilstein/REAXYS Number:
4060813
MDL number:
Assay:
≥97.0% (AT)
Form:
solid
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form

solid

InChI key

RVEJRPJGKXTQIF-UHFFFAOYSA-M

InChI

1S/C20H18OP.ClH/c21-16-17-22(18-10-4-1-5-11-18,19-12-6-2-7-13-19)20-14-8-3-9-15-20;/h1-16H,17H2;1H/q+1;/p-1

SMILES string

[Cl-].O=CC[P+](c1ccccc1)(c2ccccc2)c3ccccc3

assay

≥97.0% (AT)

reaction suitability

reaction type: C-C Bond Formation

mp

209-212 °C (dec.) (lit.)

functional group

aldehyde, phosphine

storage temp.

2-8°C

Quality Level

Application

Reactant for:
  • Hydroazidation reactions in preparation of a-azido alcohols
  • Preparation of prodrug (2-hydroxyamino-vinyl)-triphenyl-phosphonium (HVTP) inhibitor of peroxidase activity and apoptosis
  • Intramolecular [4 + 3] cycloaddition reactions

pictograms

CorrosionExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Jamal Bouitbir et al.
Toxicology, 426, 152281-152281 (2019-08-25)
Sunitinib is cardiotoxic, but the mechanisms are not entirely clear. We aimed to enlarge our knowledge about the role of mitochondria in cardiac toxicity of sunitinib in vitro and in vivo. For this reason, we studied the toxicity of sunitinib

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