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Merck
CN

480789

Bismuth(III) subsalicylate

99.9% trace metals basis

Synonym(s):

Bismuth oxysalicylate, Bismuth subsalicylate, Bismuth(III) salicylate basic

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About This Item

Linear Formula:
HOC6H4COOBiO
CAS Number:
Molecular Weight:
362.09
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12161600
EC Number:
238-953-1
MDL number:
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Quality Level

assay

99.9% trace metals basis

reaction suitability

core: bismuth, reagent type: catalyst

mp

>350 °C (lit.)

SMILES string

O[Bi]1OC(=O)c2ccccc2O1

InChI

1S/C7H6O3.Bi.H2O/c8-6-4-2-1-3-5(6)7(9)10;;/h1-4,8H,(H,9,10);;1H2/q;+3;/p-3

InChI key

ZREIPSZUJIFJNP-UHFFFAOYSA-K

General description

Bismuth(III) subsalicylate (BSS) is mainly used in bismuth-based medicines for treating gastrointestinal disorders and diarrhea.

Application

  • Use of ferric chloride to identify salicylate-containing poisons.: This study explores the use of ferric chloride to detect salicylate compounds, including Bismuth subsalicylate, highlighting its significance in toxicological screenings and emergency treatments. (Hoffman RJ et al., 2002).
  • Effect of pepper and bismuth subsalicylate on gastric pain and surface hydrophobicity in the rat.: Investigates the effects of Bismuth subsalicylate on gastric pain and stomach lining properties, providing insights into its gastroprotective mechanisms. (Lichtenberger LM et al., 1998).
  • The coccoid forms of Helicobacter pylori. Criteria for their viability.: Examines the effectiveness of Bismuth subsalicylate in targeting different morphological forms of Helicobacter pylori, contributing to its role in eradication therapies. (Bode G et al., 1993).
  • Bismuth therapy in gastrointestinal diseases.: A comprehensive review of the therapeutic applications of Bismuth subsalicylate in treating various gastrointestinal disorders, underscoring its pharmacological benefits and safety profile. (Gorbach SL, 1990).


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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D W Bierer
Reviews of infectious diseases, 12 Suppl 1, S3-S8 (1990-01-01)
Pepto-Bismol, which contains bismuth subsalicylate (BSS) as the active ingredient, has been marketed in the United States for more than 80 years. In the gastrointestinal tract, BSS is converted to salicylic acid and insoluble bismuth salts. The salicylate portion of
Raúl León Barúa
Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru, 30(2), 148-152 (2010-07-21)
In the present paper, the author reminds investigations performed, since forty-four years ago, to clarify the etiopathogenesis and to improve the diagnosis and treatment of the flatulence syndrome.
Michael S Leib et al.
Journal of veterinary internal medicine, 21(6), 1185-1192 (2008-01-17)
Helicobacter pylori is a common cause of gastritis and peptic ulcers in humans. Many dogs, including those with gastritis and chronic vomiting, are infected with Helicobacter spp. Triple antimicrobial therapy will eradicate Helicobacter infection, improve gastritis, and reduce clinical signs.



Global Trade Item Number

SKUGTIN
480789-500G04061832388397
480789-100G04061832388380