Quality Segment
assay
97%
refractive index
n20/D 1.449 (lit.)
bp
52 °C/2 mmHg (lit.)
density
1.6 g/mL at 25 °C (lit.)
functional group
fluoro, isocyanate
storage temp.
2-8°C
SMILES string
Fc1c(F)c(F)c(N=C=O)c(F)c1F
InChI
1S/C7F5NO/c8-2-3(9)5(11)7(13-1-14)6(12)4(2)10
InChI key
QXLDBWRLZDBVGF-UHFFFAOYSA-N
General description
Pentafluorophenyl isocyanate (PFPI), an aryl isocyanate, is an N-protecting reagent. The photoinduced intermolecular carbamoylation of tertiary ethereal C-H bond of fused bicyclic system using PFPI/benzophenone has been reported. Reacting wood polymers with PFPI can make them resistant to fungal attack by forming a stable carbamate bond.
Application
Pentafluorophenyl isocyanate may be used in the preparation of:
- pentafluorophenyl end-capped poly(ethylene glycol) (PF-PEG-PF)
- 9-O-(pentafluorophenylcarbamoyl)quinine
- 9-O-(tert-butyldimethylsilyl)-10-(pentafluorophenylcarbamoyloxy)-6′-methoxy-11-norcinchonan-9-ol
- substituted 2,6-ethynylpyridine bisphenylurea scaffolds
- novel O-xylyl bridged hexaurea receptor for atmospheric CO2 uptake
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
230.0 °F - closed cup
flash_point_c
110 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter