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Hexacosanoic acid

Name: Hexacosanoic acid
Brand: ALDRICH

technical, ≥90% (GC)

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Synonym(s):

Cerotic acid, Cerotinic acid

Linear Formula:

CH₃(CH₂)₂₄COOH

CAS Number:

506-46-7

Molecular Weight:

396.69

Beilstein:

1799681

EC Number:

208-040-2

MDL number:

MFCD00002811

PubChem Substance ID:

57651361

grade

technical

Assay

≥90% (GC)

mp

84-88 °C

SMILES string

CCCCCCCCCCCCCCCCCCCCCCCCCC(O)=O

InChI

1S/C26H52O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26(27)28/h2-25H2,1H3,(H,27,28)

InChI key

XMHIUKTWLZUKEX-UHFFFAOYSA-N

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Related Categories

Organic Building Blocks

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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The prenatal diagnosis of adrenoleukodystrophy. Demonstration of increased hexacosanoic acid levels in cultured amniocytes and fetal adrenal gland.

H W Moser et al.

Pediatric research, 16(3), 172-175 (1982-03-01)

Amniocentesis was performed in two women heterozygous for adrenoleukodystrophy (ALD). One fetus was male, and the hexacosanoic acid (C26) level in the cultured amniotic cells was 0.808 microgram per mg of protein, compared to 0.104 +/- 0.069 (S.D.) in controls.

A two-year trial of oleic and erucic acids ("Lorenzo's oil") as treatment for adrenomyeloneuropathy.

P Aubourg et al.

The New England journal of medicine, 329(11), 745-752 (1993-09-09)

Adrenomyeloneuropathy is an X-linked recessive disorder characterized by myelopathy, peripheral neuropathy, and cerebral demyelination, which develop in association with the accumulation of very-long-chain fatty acids. The administration of oleic and erucic acids inhibits the synthesis of very-long-chain fatty acids. Recently

Plasmalogens participate in very-long-chain fatty acid-induced pathology.

Pedro Brites et al.

Brain : a journal of neurology, 132(Pt 2), 482-492 (2008-11-22)

Peroxisomes are organelles responsible for multiple metabolic pathways including, the biosynthesis of plasmalogens, a class of phospholipids, and the beta-oxidation of very-long-chain fatty acids (VLCFA). Lack of peroxisomes or dysfunction in any of their normal functions is the cellular basis

A fast method for the identification of Mycobacterium tuberculosis in sputum and cultures based on thermally assisted hydrolysis and methylation followed by gas chromatography-mass spectrometry.

Erwin Kaal et al.

Journal of chromatography. A, 1216(35), 6319-6325 (2009-07-28)

A fast gas chromatography-mass spectrometry (GC-MS) method with minimum sample preparation is described for early diagnosis of tuberculosis (TB). The automated procedure is based on the injection of sputum samples which are then methylated inside the GC injector using thermally

Adrenomyeloneuropathy presenting as Addison's disease in childhood.

A Sadeghi-Nejad et al.

The New England journal of medicine, 322(1), 13-16 (1990-01-04)

Adrenoleukodystrophy, a sex-linked peroxisomal disorder that results in the impaired oxidation of long-chain saturated fatty acids and causes neurologic impairment, is a rare cause of Addison's disease in children. Adrenomyeloneuropathy is the name given to a biochemically identical but milder

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