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Poly(D,L-lactide-co-glycolide)

average Mw 5,000-15,000, lactide:glycolide (50:50)

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Synonym(s):
PLGA
Linear Formula:
[C3H4O2]x[C2H2O2]y
MDL number:
MFCD00131930
PubChem Substance ID:
24877804

feed ratio

lactide:glycolide (50:50)

mol wt

average Mw 5,000-15,000

inherent viscosity

0.15-0.25 dL/g(lit.)

transition temp

Tg (DSC) 24 °C (onset)

SMILES string

OCC(O)=O.CC(O)C(O)=O

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Features and Benefits

Controlled release of bioactive agents, sutures and bioabsorbable implantable devices.

Physical form

Biocompatible, biodegradable polymer.

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Claus G Madsen et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 92, 1-7 (2015-02-11)
This study describes how protein release from polymer matrices correlate with simple measurements on the intrinsic viscosity of the polymer solutions used for casting the matrices and calculations of the solubility parameters of polymers and solvents used. Matrices of poly(dl-lactide-co-glycolide)

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