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534579

(R)-(−)-2-Amino-1-pentanol

97%

Synonym(s):

D-Norvalinol

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About This Item

Linear Formula:
CH3(CH2)2CH(NH2)CH2OH
CAS Number:
Molecular Weight:
103.16
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352116
MDL number:
Assay:
97%
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Quality Segment

assay

97%

optical activity

[α]20/D −17°, c = 1 in chloroform

mp

44-48 °C (lit.)

functional group

amine, hydroxyl

SMILES string

CCC[C@@H](N)CO

InChI

1S/C5H13NO/c1-2-3-5(6)4-7/h5,7H,2-4,6H2,1H3/t5-/m1/s1

InChI key

ULAXUFGARZZKTK-RXMQYKEDSA-N

Application

(R)-(-)-2-Amino-1-pentanol can be used as a chiral building block to prepare:
  • A key intermediate, (R)-N-(p-toluenesulfonyl)-2-propylaziridine, which is utilized in the total synthesis of (R)-1-(benzofuran-2-yl)-2-propylaminopentane.
  • (R)-N-benzyloxycarbonyl-aminoaldehydes as potential substrates for dihydroxyacetone phosphate (DHAP)-dependent aldolases.
  • (R)-2-((2-Aminoquinazolin-4-yl)amino)pentan-1-ol as a potent dual toll-like receptor and modulator.



Pictograms

Exclamation mark

Signal Word

Warning

Hazard Codes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

10 - Combustible liquids

Flash Point (°F)

204.8 °F - closed cup

Flash Point (°C)

96 °C - closed cup

PPE (personal protective equipment)

Eyeshields, Gloves, type ABEK (EN14387) respirator filter



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