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Merck
CN

53588

Homopiperazine-1,4-bis(2-ethanesulfonic acid)

Synonym(s):

Hexahydro-1H-1,4-diazepine-1,4-bis(2-ethanesulfonic acid), Homo-PIPES

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About This Item

Empirical Formula (Hill Notation):
C9H20N2O6S2
CAS Number:
202185-84-0
Molecular Weight:
316.39
NACRES:
NA.22
PubChem Substance ID:
57651422
UNSPSC Code:
12352100
MDL number:
MFCD00467737
Form:
solid

Key Documents

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InChI

1S/C9H20N2O6S2/c12-18(13,14)8-6-10-2-1-3-11(5-4-10)7-9-19(15,16)17/h1-9H2,(H,12,13,14)(H,15,16,17)

SMILES string

OS(=O)(=O)CCN1CCCN(CC1)CCS(O)(=O)=O

InChI key

QZTMPPUJIVQNKS-UHFFFAOYSA-N

form

solid

impurities

≤5% water

functional group

sulfonic acid

Quality Level

100

Related Categories

General description

Homopiperazine-1,4-bis(2-ethanesulfonic acid) is used as a buffer in experiments involving plant cells at low pH.

Application

  • Evaluation of buffers toxicity in plant cells: Homopiperazine-1,4-bis(2-ethanesulfonic acid) was evaluated for its suitability as a buffer in tobacco cell studies at low pH, highlighting its low toxicity and effectiveness in maintaining stable pH environments crucial for plant cell biology experiments (Borgo, 2017).
  • Proteomic analysis under stress conditions: This buffer was used in maintaining pH during the proteomic analysis of radicles from seeds treated with aluminum, showcasing its utility in complex biological assays and environmental stress studies (Okekeogbu et al., 2014).

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

hcodes

H312,H314

Hazard Classifications

Acute Tox. 4 Dermal - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL2570
BCCK2871
BCCF5994
BCCF6042
BCBZ5399

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Doris Pester et al.
PloS one, 7(3), e32583-e32583 (2012-03-14)
Pathogen entry through host blossoms is the predominant infection pathway of the gram-negative bacterium Erwinia amylovora leading to manifestation of the disease fire blight. Like in other economically important plant pathogens, E. amylovora pathogenicity depends on a type III secretion
Evaluation of buffers toxicity in tobacco cells: Homopiperazine-1, 4-bis (2-ethanesulfonic acid) is a suitable buffer for plant cells studies at low pH
Borgo L
Plant Physiology and Biochemistry, 115, 119-125 (2017)
Florian Schmidt et al.
Nature, 562(7727), 380-385 (2018-10-05)
The ability to record transcriptional events within a cell over time would help to elucidate how molecular events give rise to complex cellular behaviours and states. However, current molecular recording technologies capture only a small set of defined stimuli. Here

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