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Merck
CN

540048

(R)-(+)-Propylene oxide

99%

Synonym(s):

(R)-(+)-1,2-Epoxypropane, (R)-(+)-Methyloxirane

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About This Item

Empirical Formula (Hill Notation):
C3H6O
CAS Number:
Molecular Weight:
58.08
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
79764
Assay:
99%
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Quality Segment

assay

99%

optical activity

[α]20/D +14°, neat

reaction suitability

reagent type: chrial catalyst

refractive index

n20/D 1.366 (lit.)

bp

33-34 °C (lit.)

density

0.829 g/mL at 20 °C (lit.)

functional group

ether

SMILES string

C[C@@H]1CO1

InChI

1S/C3H6O/c1-3-2-4-3/h3H,2H2,1H3/t3-/m1/s1

InChI key

GOOHAUXETOMSMM-GSVOUGTGSA-N

Application

(R)-(+)-Propylene oxide is commonly employed as a chiral building block or intermediate in the synthesis of chiral compounds. For example, it can be used to synthesize cyclic propylene carbonate by the reaction with CO2 in the presence of a chiral catalyst. It is also used as a starting material for the preparation of magnetic resonance (MR) contrast agents that can be used for in vivo detection of β-galactosidase.


Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Flam. Liq. 1 - Muta. 1B - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

3 - Flammable liquids

WGK

WGK 3

Flash Point (°F)

-40.0 °F - Pensky-Martens closed cup

Flash Point (°C)

-40 °C - Pensky-Martens closed cup

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves



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