545953
1-Aminohydantoin hydrochloride
98%
Synonym(s):
1-Amino-2,4-imidazolidinedione hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C3H5N3O2 · HCl
CAS Number:
Molecular Weight:
151.55
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3699376
Assay:
98%
InChI
1S/C3H5N3O2.ClH/c4-6-1-2(7)5-3(6)8;/h1,4H2,(H,5,7,8);1H
SMILES string
Cl[H].NN1CC(=O)NC1=O
InChI key
WEOHANUVLKERQI-UHFFFAOYSA-N
assay
98%
mp
201-205 °C (lit.)
Quality Level
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Application
1-Aminohydantoin hydrochloride may be used as one of the reactants in the synthesis of (E)-1-(2-hydroxybenzylideneamino)imidazolidine-2,4-dione, dantrolene and dantrolene sodium.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Yuli Xie et al.
Bioorganic & medicinal chemistry letters, 18(9), 2840-2844 (2008-04-25)
We report here a class of thiazolidine-2,4-diones and 2-thioxothiazolidin-4-ones as potent inhibitors of the lymphoid specific tyrosine phosphatase (Lyp) identified from high throughput screens. Chemical modification by incorporating the known phosphotyrosine (pTyr) mimics led to the discovery of a salicylate-based
Abdelselam Ali et al.
Bioorganic & medicinal chemistry letters, 20(2), 649-652 (2009-12-08)
A series of hydrazonotrifluorosulfonanilide derivatives were synthesized and evaluated for in vitro activity against the ectoparasites Ctenocephalides felis and Rhipicephalus sanguineus. Some compounds with excellent activity against tick were identified.
Ascorbic Acid as an Initiator for the Direct C H Arylation of (Hetero) arenes with Anilines Nitrosated In Situ
Crisostomo, Fernando Pinacho, Tomas Martin, and Romen Carrillo
Angewandte Chemie (International Edition in English), 53.8 , 2181-2185 (2014)
Crystal structure of (E)-1-(2-hydroxybenzylideneamino) imidazolidine-2, 4-dione, C10H9N3O3.
Hu, Lei, et al.
Zeitschrift fur Kristallographie, 230(2), 111-112 (2015)
Johann Leban et al.
Bioorganic & medicinal chemistry, 16(8), 4579-4588 (2008-03-04)
Peptide-semicarbazones derived from Z-Trp-Trp-Phe-aldehyde inhibit the chymotryptic activity of the human proteasome at nanomolar concentrations, but are less active in a NFkappaB reporter gene assay. Cyclic semicarbazones, in contrast, combine a strong inhibitory effect on the enzyme with an inhibition
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