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549835

2,4,6-Tris(dimethylamino)-1,3,5-triazine

Name: 2,4,6-Tris(dimethylamino)-1,3,5-triazine
Brand: ALDRICH

96%

Synonym(s):

Altretamine, Hexamethylmelamine

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About This Item

Empirical Formula (Hill Notation):

C₉H₁₈N₆

CAS Number:

645-05-6

Molecular Weight:

210.28

NACRES:

NA.22

PubChem Substance ID:

24874728

UNSPSC Code:

12352100

EC Number:

211-428-4

MDL number:

MFCD00549245

Assay:

96%

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Properties

Quality Level

100

assay

96%

mp

171-175 °C (lit.)

functional group

amine

SMILES string

CN(C)c1nc(nc(n1)N(C)C)N(C)C

InChI

1S/C9H18N6/c1-13(2)7-10-8(14(3)4)12-9(11-7)15(5)6/h1-6H3

InChI key

UUVWYPNAQBNQJQ-UHFFFAOYSA-N

Description

General description

2,4,6-Tris(dimethylamino)-1,3,5-triazine exhibits antitumor activity.

pictograms

GHS07

signalword

Warning

hcodes

H302,H315,H319,H335

pcodes

P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Triazines and related products. Part 26. Synthesis and chemistry of bicyclic analogues of the antitumour drug 2, 4, 6-tris (dimethylamino)-1, 3, 5-triazine (hexamethylmelamine).

Langdon SP, et al.

Journal of the Chemical Society. Perkin Transactions 1, 993-998 (1984)

Hexamethylmelamine as consolidation treatment for patients with advanced epithelial ovarian cancer in complete response after first-line chemotherapy.

Yong Soon Kwon et al.

Journal of Korean medical science, 24(4), 679-683 (2009-08-06)

The aim of this study was to assess the efficacy of consolidation therapy with hexamethylmelamine (HMM) in patients with advanced epithelial ovarian cancer (EOC). Patients treated at our hospital between January 1997 and November 2006 and in documented clinical complete

Solvent, emulsifier and drug concentration factors in poly(D,L-lactic acid) microspheres containing hexamethylmelamine.

M Hariharan et al.

Journal of microencapsulation, 19(1), 95-109 (2002-01-29)

Biodegradable poly(D,L-lactic acid) (PLA) microspheres containing hexamethylmelamine (HMM) were developed for potential use in chemoembolization and intraperitoneal implantation. The emulsion-solvent-evaporation/extraction method was used to prepare 15 formulations with different drug/polymer ratios, solvent compositions and emulsifer concentrations in the continuous aqueous

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Global Trade Item Number

SKU	GTIN
549835-25G	04061833398968