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549975

3-(Diethylamino)propylamine

Name: 3-(Diethylamino)propylamine
Brand: ALDRICH

Synonym(s):

N,N-Diethyl-1,3-diaminopropane, N,N-Diethyl-1,3-propanediamine, DEAPA

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About This Item

Linear Formula:

(C₂H₅)₂N(CH₂)₃NH₂

CAS Number:

104-78-9

Molecular Weight:

130.23

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24874737

EC Number:

203-236-4

Beilstein/REAXYS Number:

741879

MDL number:

MFCD00008218

Assay:

99% (GC)

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Properties

vapor density

4.4 (vs air)

vapor pressure

19.5 mmHg ( 70 °C)

assay

99% (GC)

autoignition temp.

419 °F

expl. lim.

11.6 %

refractive index

n20/D 1.4416 (lit.)

bp

159 °C (lit.)

density

0.826 g/mL at 25 °C (lit.)

functional group

amine

SMILES string

CCN(CC)CCCN

InChI

1S/C7H18N2/c1-3-9(4-2)7-5-6-8/h3-8H2,1-2H3

InChI key

QOHMWDJIBGVPIF-UHFFFAOYSA-N

Description

General description

3-(Diethylamino)propylamine (3-(diethylamino)-1-propylamine, DEAPA) is a diamine.

Application

3-(Diethylamino)propylamine may be used in the preparation of:

Biocompatible polyampholyte-coated (poly(acrylic acid)-co-3-(diethylamino)-propylamine magnetite nanoparticles (PAMNPs).
Hyaluronic acid grafted with 3-diethylaminopropyl (DEAP) group (HA-g-DEAP) nanoparticles for use as a drug delivery vehicle.
DEAPA-modified poly(vinyl alcohol) (PVA) polymers that can be employed in gene silencing.

It may also be used to introduce cationic groups during the surface modification of microfibrillated cellulose (MFC).

pictograms

GHS02,GHS06,GHS05

signalword

Danger

hcodes

H226,H302,H311,H314,H317,H335

pcodes

P210 - P233 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

flash_point_f

125.6 °F - closed cup

flash_point_c

52 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品

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Chemical surface modifications of microfibrillated cellulose.

Stenstad P, et al.

Cellulose, 15(1), 35-45 (2008)

Low toxicity and long circulation time of polyampholyte-coated magnetic nanoparticles for blood pool contrast agents.

Wang Qi, et al.

Scientific Reports, 5, 7774-7774 (2015)

Amine-modified poly(vinyl alcohol)s as non-viral vectors for siRNA delivery: effects of the degree of amine substitution on physicochemical properties and knockdown efficiency.

Juliane Nguyen et al.

Pharmaceutical research, 27(12), 2670-2682 (2010-09-18)

The objective of this study was to investigate how the degree of amine substitution of amine-modified poly(vinyl alcohol) (PVA) affects complexation of siRNA, protection of siRNA against degrading enzymes, intracellular uptake and gene silencing. A series of DEAPA-PVA polymers with

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Global Trade Item Number

SKU	GTIN
549975-500ML	04061836827526
549975-2L	04061832575674
549975-100ML	04061836827519