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Merck
CN

56413

2-Pyridinol 1-oxide

≥98.0% (N)

Synonym(s):

1-Hydroxy-2-pyridone, 2-Hydroxypyridine 1-oxide, HOPO

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About This Item

Empirical Formula (Hill Notation):
C5H5NO2
CAS Number:
Molecular Weight:
111.10
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
EC Number:
236-100-8
Beilstein/REAXYS Number:
1422545
MDL number:
Assay:
≥98.0% (N)
Form:
solid
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Quality Segment

assay

≥98.0% (N)

form

solid

mp

147-152 °C

SMILES string

Oc1cccc[n+]1[O-]

InChI

1S/C5H5NO2/c7-5-3-1-2-4-6(5)8/h1-4,7H

InChI key

JVHZMYAXZUIZKS-UHFFFAOYSA-N

General description

2-Pyridinol 1-oxide (HOPO) is a peptide coupling agent used as a subsititue for HOBt. It can form stable chelate complexes with transition metal ions.

Application

2-Pyridinol 1-oxide can be used:    
  • To fabricate gold electrodes for the electrochemical determination of europium using cyclic voltammetry.        
  • To prepare polymeric nickel (II) complex of 2-hydroxypyridine-N-oxide.
  • In the synthesis of 1-methoxypyrid-4-one in the presence of sodium methoxide and methyl toluene-9-sulphonate.


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

212.0 °F - closed cup

flash_point_c

100 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves



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