574740
trans-Diamminetetrachloroplatinum(IV)
≥99.9% trace metals basis
Synonym(s):
trans- Tetrachlorodiammineplatinum
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About This Item
Linear Formula:
Pt(NH3)2Cl4
CAS Number:
Molecular Weight:
370.95
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12352302
MDL number:
Assay:
≥99.9% trace metals basis
Form:
powder
assay
≥99.9% trace metals basis
form
powder
mp
>300 °C (lit.)
SMILES string
N.N.Cl[Pt](Cl)(Cl)Cl
InChI
1S/4ClH.2H3N.Pt/h4*1H;2*1H3;/q;;;;;;+4/p-4
InChI key
RBHOYUZKIANPPG-UHFFFAOYSA-J
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Sens. 1
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Articles
Plasmonic nanoparticles have unique optical properties that can be tailored to suit a variety of applications in the biotechnology1–8 and electronics9–16 industries.
A C Plooy et al.
Cancer research, 44(5), 2043-2051 (1984-05-01)
Several effects of four diamminechloroplatinum compounds (II and IV) in Chinese hamster ovary cells were studied. The two cis-compounds [cis-diamminedichloroplatinum(II) and cis-diamminetetrachloroplatinum(IV)] are known to possess antitumor activity, whereas the two trans-stereoisomers [trans-diamminedichloroplatinum(II) and trans-diamminetetrachloroplatinum(IV)] are inactive. When the effects
M Defais et al.
Chemico-biological interactions, 74(3), 343-352 (1990-01-01)
DNA strand breaks were observed in bacteria treated with Pt(IV) but not Pt(II) antitumor compounds by two methods. First, compounds which cause DNA strand breaks produced an SOS induction signal which was detected by a rapid bacterial assay. In addition
H Razaka et al.
Chemico-biological interactions, 60(2), 207-215 (1986-11-01)
After exposure of bacteria to equal concentrations of cis-diamminedichloroplatinum(II) (DDP) and cis-diamminetetrachloroplatinum(IV) (DTP), the intracellular concentration of DTP was an order of magnitude greater than DDP. However, at identical intracellular drug concentrations, the Pt(IV) compound formed only half as many
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 574740-1G | 04061826697238 |