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Merck
CN

592293

2-Methoxyethyl chloroformate

Synonym(s):

(2-Methoxyethoxy)carbonyl chloride, (Chloro)(2-methoxyethoxy)methanone, 2-Methoxyethyl carbonochloridate, Chloroformic acid 2-methoxyethyl ester

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About This Item

Linear Formula:
CH3OCH2CH2OCOCl
CAS Number:
Molecular Weight:
138.55
UNSPSC Code:
12352100
PubChem Substance ID:
EC Number:
211-026-9
MDL number:
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InChI key

NDYYWMXJZWHRLZ-UHFFFAOYSA-N

InChI

1S/C4H7ClO3/c1-7-2-3-8-4(5)6/h2-3H2,1H3

SMILES string

COCCOC(Cl)=O

refractive index

n20/D 1.4200 (lit.)

bp

157-158 °C (lit.)

density

1.192 g/mL at 25 °C (lit.)

storage temp.

2-8°C

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Application

Reactant for:
  • Preparation of N-bridged bicyclic sulfonamides as inhibitors of γ-secretase
  • Preparation of dimethoxyethyl azodicarboxylate via amidation/oxidation and application to Mitsunobu reaction
  • Regioselective, stereoselective, and kinetically-controlled nickel-catalyzed cyanoesterification of allenes chloroformates and TMSCN
  • Preparation of amino carboxamidobenzothiazoles as Lck inhibitors
  • Preparation of nonracemic spirooxindoles using a stereoselective three-component coupling reaction as the key step and using acylation reactions to add structural diversity

pictograms

FlameCorrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

138.0 °F - closed cup

flash_point_c

58.9 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

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