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About This Item
Linear Formula:
(13CH3)213CH13CH213CH(NH2)13CO2H
CAS Number:
Molecular Weight:
137.13
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.12
isotopic purity
98 atom % 13C
Quality Level
Assay
95% (CP)
form
solid
optical activity
[α]25/D +14.5°, c = 2 in 5 M HCl
technique(s)
protein expression: suitable
mp
>300 °C (lit.)
mass shift
M+6
SMILES string
[13CH3][13CH]([13CH3])[13CH2][13C@H](N)[13C](O)=O
InChI
1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1/i1+1,2+1,3+1,4+1,5+1,6+1
InChI key
ROHFNLRQFUQHCH-IQUPZBQQSA-N
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General description
Leucine is a non-polar ketogenic amino acid. It can be metabolised to acetoacetate and acetyl coenzyme A. Isotope labeled amino acids are required for the production of isotopically labeled proteins.
Packaging
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Garrett RH and Grisham CM
Biochemistry (2012)
The incorporation of radioactive amino acids into proteins of the microsome fraction of guinea-pig liver at very short time intervals after administration.
Simkin JL and Sutton CR
The Biochemical Journal, 77, 489-492 (1960)
Harvey RA, et al.
Biochemistry (Lippincott's illustrated reviews) (2011)
Isotope labeling for solution and solid-state NMR spectroscopy of membrane proteins.
Verardi R, et al.
Advances in Experimental Medicine and Biology, 992, 35-62 (2012)
Incorporation of radioactive amino acids into proteins of the microsome fraction of guinea-pig liver in a cell-free system.
SIMKIN JL and WORK TS
The Biochemical Journal, 67, 617-624 (1957)
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