608092
L-Isoleucine-13C6,15N
98 atom % 15N, 98 atom % 13C, 95% (CP)
Synonym(s):
SILAC Amino Acid, (2S,3S)-2-Amino-3-methylpentanoic acid-13C6,15N, 13C and 15N Labeled L-isoleucine
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About This Item
Linear Formula:
13C2H513CH(13CH3)13CH(15NH2)13CO2H
CAS Number:
Molecular Weight:
138.12
NACRES:
NA.12
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Isotopic purity:
98 atom % 13C, 98 atom % 15N
Assay:
95% (CP)
Mass shift:
M+7
Form:
solid
Quality Level
isotopic purity
98 atom % 13C, 98 atom % 15N
assay
95% (CP)
form
solid
optical activity
[α]25/D +40.0°, c = 2 in 5 M HCl
technique(s)
bio NMR: suitable, protein expression: suitable
mp
168-170 °C (lit.)
mass shift
M+7
SMILES string
[13CH3][13CH]([13CH3])[13CH2][13C@H]([15NH2])[13C](O)=O
InChI
1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1/i1+1,2+1,3+1,4+1,5+1,6+1,7+1
InChI key
ROHFNLRQFUQHCH-HUEJSTCGSA-N
General description
L-isoleucine is an essential amino acid that is synthesized from threonine. It is a branched-chain hydrophobic amino acid. L-isoleucine is an isomer of L-leucine.
Application
L-Isoleucine-13C6,15N is used in the immunocapture isotope dilution mass spectrometry (IC-IDMS) to evaluate the suitability of the underlying monoclonal andpolyclonal antibodies (mAbs and pAbs) for new vaccine quantification.
Packaging
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Carrie L Pierce et al.
Vaccine, 35(37), 5011-5018 (2017-08-05)
As a result of recent advances in mass spectrometry-based protein quantitation methods, these techniques are now poised to play a critical role in rapid formulation of pandemic influenza vaccines. Analytical techniques that have been developed and validated on seasonal influenza
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 608092-100MG | 04061832690742 |
| 608092-250MG | 04061842205080 |