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608203

Sigma-Aldrich

D-Glucose-12C6, 16O6

99.9 atom % 16O, 99.9 atom % 12C

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Synonym(s):
D-(+)-Glucose, Dextrose
Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
50-99-7
Molecular Weight:
180.16
Beilstein:
1724615
EC Number:
200-075-1
MDL number:
MFCD00063774
PubChem Substance ID:
329759239

description

13C depleted
18O depleted

isotopic purity

99.9 atom % 12C
99.9 atom % 16O

form

crystalline powder

optical activity

[α]25/D +52.5 to +53°, c = 10 in water + trace NH4OH

mp

150-152 °C (lit.)

solubility

H2O: soluble

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

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Ragadeepthi Tunduguru et al.
Biochemical pharmacology, 92(2), 380-388 (2014-09-10)
Skeletal muscle accounts for ∼ 80% of postprandial glucose clearance, and skeletal muscle glucose clearance is crucial for maintaining insulin sensitivity and euglycemia. Insulin-stimulated glucose clearance/uptake entails recruitment of glucose transporter 4 (GLUT4) to the plasma membrane (PM) in a
Yu-ting Alex Chiang et al.
American journal of physiology. Endocrinology and metabolism, 306(7), E707-E722 (2013-12-26)
p21-Activated protein kinases (PAKs) are centrally involved in a plethora of cellular processes and functions. Their function as effectors of small GTPases Rac1 and Cdc42 has been extensively studied during the past two decades, particularly in the realms of cell
Lars P Bechmann et al.
Journal of hepatology, 56(4), 952-964 (2011-12-17)
It is widely known that the liver is a central organ in lipogenesis, gluconeogenesis and cholesterol metabolism. However, over the last decades, a variety of pathological conditions highlighted the importance of metabolic functions within the diseased liver. As observed in
James C Lo et al.
Cell, 158(1), 41-53 (2014-07-06)
A hallmark of type 2 diabetes mellitus (T2DM) is the development of pancreatic β cell failure, which results in insulinopenia and hyperglycemia. We show that the adipokine adipsin has a beneficial role in maintaining β cell function. Animals genetically lacking
Dov B Ballak et al.
Nature communications, 5, 4711-4711 (2014-09-04)
Cytokines of the IL-1 family are important modulators of obesity-induced inflammation and the development of systemic insulin resistance. Here we show that IL-1 family member IL-37, recently characterized as an anti-inflammatory cytokine, ameliorates obesity-induced inflammation and insulin resistance. Mice transgenic
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