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Merck
CN

617474

Sigma-Aldrich

Deuterium

99.9 atom % D

Synonym(s):

D2

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About This Item

Linear Formula:
D2
CAS Number:
Molecular Weight:
4.03
MDL number:
UNSPSC Code:
12352101
PubChem Substance ID:
NACRES:
NA.12
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vapor density

0.07 (vs air)

Quality Level

isotopic purity

99.9 atom % D

Assay

99.996% (CP)

bp

-249.5 °C (lit.)

density

0.169 g/mL at -250.9 °C (liq)(lit.)
0.165 g/L at 25 °C (gas)

mass shift

M+2

SMILES string

[2H][2H]

InChI

1S/H2/h1H/i1+1D

InChI key

UFHFLCQGNIYNRP-VVKOMZTBSA-N

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General description

Deuterium 99.9 atom % D is a high-purity isotope product with a unique chemical profile that belongs to the class of isotopes. Produced by Sigma-Aldrich, we are committed to providing quality isotope products and a reliable supply chain. Available in industrial and pre-pack quantities.

Application

- Deuterium labeling for metabolic and pharmacokinetic studies
- synthesis of deuterated reference standards
- Isotope effect investigations in reaction mechanisms
- Pharmaceutical formulation development

Features and Benefits

Features
- High-quality solvent for analytical applications
- Improves accuracy in structural analyses
- Non-toxic and environmentally friendly
- Supports a variety of research applications

Benefits
- Ensures high-quality results in analytical experiments
- Increases reliability of obtained data
- Facilitates understanding of complex interactions
- Supports effective therapy development

Packaging

All gas volumes are quoted at Standard Temperature and Pressure (STP) and not at Normal Temperature and Pressure (NTP). One STP Liter is 7.7% more gas than one NTP Liter.
Standard products are packaged in a 450 mL carbon steel lecture bottle with brass CGA 110/180 valve. Nominal gas pressures at 21ºC are 850 psig for 25 L and 1570 psig for 45 L. Care must be taken when extracting this product from the cylinder.
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Other Notes

Stainless steel control valves Z146951, Z187224 or either of stainless steel regulators Z148504 and Z148512 is recommended.
PTFE sealing washers GCA inlet size 180 Z146994
PTFE sealing washers CGA inlet size 110 Z146986

Pictograms

FlameGas cylinder

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Flam. Gas 1 - Press. Gas Compr. Gas

Storage Class Code

2A - Gases

WGK

nwg

Flash Point(F)

<-238.0 °F - closed cup

Flash Point(C)

< -150 °C - closed cup

Regulatory Information

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Martin Byrdin et al.
Biochimica et biophysica acta, 1655(1-3), 64-70 (2004-04-22)
We review our work on electron transfer and proton dynamics during photoactivation in DNA photolyase from E. coli and discuss a recent theoretical study on this issue. In addition, we present unpublished data on the charge recombination between the fully
Srinath Krishnamurthy et al.
Biochimica et biophysica acta, 1834(6), 1215-1221 (2013-03-19)
cAMP signaling is a fundamental cellular process necessary for mediating responses to hormonal stimuli. In contrast to cAMP-dependent activation of protein kinase A (PKA), an important cellular target, far less is known on termination in cAMP signaling, specifically how phosphodiesterases
Ying Zhang et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(36), 14604-14609 (2013-08-21)
Probing the conformational changes of amyloid beta (Aβ) peptide aggregation is challenging owing to the vast heterogeneity of the resulting soluble aggregates. To investigate the formation of these aggregates in solution, we designed an MS-based biophysical approach and applied it
Michael Landreh et al.
The FEBS journal, 278(20), 3815-3821 (2011-06-15)
The study of protein structure and function has evolved to become a leading discipline in the biophysical sciences. Although it is not yet possible to determine 3D protein structures from MS data alone, multiple MS-based techniques can be combined to
Masaru Hoshino et al.
Biochimica et biophysica acta, 1768(8), 1886-1899 (2007-05-15)
A general method to analyze the structure of a supramolecular complex of amyloid fibrils at amino acid residue resolution has been developed. This method combines the NMR-detected hydrogen/deuterium (H/D) exchange technique to detect hydrogen-bonded amide groups and the ability of

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