Key Documents

View All Documentation

634786

(S)-(+)-N-Boc-3-pyrrolidinol

Name: (<I>S</I>)-(+)-<I>N</I>-Boc-3-pyrrolidinol
Brand: ALDRICH

97%

Synonym(s):

(S)-N-(tert-Butoxycarbonyl)-(+)-3-pyrrolidinol

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₉H₁₇NO₃

CAS Number:

101469-92-5

Molecular Weight:

187.24

NACRES:

NA.22

PubChem Substance ID:

24882649

UNSPSC Code:

12352005

MDL number:

MFCD01317839

Assay:

97%

Form:

solid

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Level

100

assay

97%

form

solid

optical activity

[α]20/D +26°, c = 1% in methanol

mp

60-64 °C (lit.)

functional group

hydroxyl

SMILES string

CC(C)(C)OC(=O)N1CC[C@H](O)C1

InChI

1S/C9H17NO3/c1-9(2,3)13-8(12)10-5-4-7(11)6-10/h7,11H,4-6H2,1-3H3/t7-/m0/s1

InChI key

APCBTRDHCDOPNY-ZETCQYMHSA-N

Description

Application

(S)-(+)-N-Boc-3-pyrrolidinol can be used as a reactant to synthesize:

tert-Butyl 3-(2-bromophenoxy)pyrrolidine-1-carboxylate, which is employed as a key intermediate in the preparation of IkB-kinase IKK2 inhibitor.
Dimethoxy-pyrrolidylquinazoline , and peptidomimetic quinoline derivatives.

pictograms

GHS06,GHS05

signalword

Danger

hcodes

H301,H315,H318,H335

pcodes

P280 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 + P310

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

新产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Discovery of selective irreversible inhibitors for Bruton?s tyrosine kinase

P Zhengying, et al.

ChemMedChem, 2(1), 58-61 (2007)

Discovery of a series of 6,7-dimethoxy-4-pyrrolidylquinazoline PDE10A inhibitors.

Thomas A Chappie et al.

Journal of medicinal chemistry, 50(2), 182-185 (2007-01-19)

A papaverine based pharmacophore model for PDE10A inhibition was generated via SBDD and used to design a library of 4-amino-6,7-dimethoxyquinazolines. From this library emerged an aryl ether pyrrolidyl 6,7-dimethoxyquinazoline series that became the focal point for additional modeling, X-ray, and

New prolyl oligopeptidase inhibitors developed from dicarboxylic acid bis(l-prolyl-pyrrolidine) amides.

Erik A A Wallén et al.

Journal of medicinal chemistry, 46(21), 4543-4551 (2003-10-03)

Isophthalic acid bis(l-prolyl-pyrrolidine) amide is a very potent prolyl oligopeptidase inhibitor, but it has a log P value of -0.2, which is very low for a compound targeted to the brain. Therefore, these types of compounds were further modified to

View All Related Papers

Global Trade Item Number

SKU	GTIN
634786-1G	04061826130025
634786-5G	04061832986562