647241
(R)-(−)-1-Methyl-3-pyrrolidinol
97%
Synonym(s):
(3R)-1-Methylpyrrolidin-3-ol, (R)-(−)-3-Hydroxy-N-methylpyrrolidine, (R)-N-Methyl-3-pyrrolidinol
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About This Item
InChI
1S/C5H11NO/c1-6-3-2-5(7)4-6/h5,7H,2-4H2,1H3/t5-/m1/s1
SMILES string
CN1CC[C@@H](O)C1
InChI key
FLVFPAIGVBQGET-RXMQYKEDSA-N
assay
97%
optical activity
[α]20/D -7°, c = 1% in chloroform
refractive index
n20/D 1.4640 (lit.)
bp
50-52 °C/1 mmHg (lit.)
density
0.921 g/mL at 25 °C (lit.)
Application
- Asymmetric synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors
- Preparation of diaryl acylaminopyrimidines as adenosine A2A antagonists
- Synthesis of analogs of istaroxime, a potent inhibitor of Na+,K+-ATPase
- Synthesis of pharmacologically active stereoisomers of N-substituted soft anticholinergics
signalword
Warning
target_organs
Respiratory system
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
158.0 °F
flash_point_c
70 °C
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
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