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677175

Pyruvic-1-13C acid

≥99 atom % 13C, ≥99% (CP)

Synonym(s):

α-Ketopropionic acid-1-13C, 2-Oxopropionic acid-1-13C, 13C Labeled pyruvic acid, Pyruvic acid-1-13C

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About This Item

Linear Formula:
CH3CO13CO2H
CAS Number:
99124-30-8
Molecular Weight:
89.05
NACRES:
NA.12
PubChem Substance ID:
329760673
UNSPSC Code:
12352106
MDL number:
MFCD10566986
Isotopic purity:
≥99 atom % 13C
Assay:
≥99% (CP)
Mass shift:
M+1
Form:
liquid
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isotopic purity

≥99 atom % 13C

Quality Level

200

assay

≥99% (CP)

form

liquid

bp

165 °C

mp

11-12 °C

density

1.281 g/mL at 25 °C

mass shift

M+1

shipped in

dry ice

storage temp.

−20°C

SMILES string

CC(=O)[13C](O)=O

InChI

1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)/i3+1

InChI key

LCTONWCANYUPML-LBPDFUHNSA-N

General description

Pyruvic-1-13C is isotopic labeled precursor of pyruvic acid.

Application

Hyperpolarized 13C-labeled pyruvate and its metabolite lactate has been used to image real time metabolic flux in solid tumors and assess tumor response to chemotherapy, radiation, and agents targeting mTOR.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

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pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1C

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 1

flash_point_f

179.6 °F - closed cup

flash_point_c

82 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
MBBD8894
MBBD9589
MBBD7217
MBBD6584
MBBD4204

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Articles

Glycolysis via the Embden-Meyerhof-Parnas Glycolytic Pathway

Review the 10 steps of glycolysis in the Embden-Meyerhof-Parnas glycolytic pathway. Easily compare reaction stages and buy the enzymes for your life science research.

Prasanta Dutta et al.
Cancer research, 73(14), 4190-4195 (2013-06-01)
Hyperpolarized (13)C magnetic resonance spectroscopy provides a unique opportunity to detect real-time metabolic fluxes as a means to measure metabolic treatment responses in vivo. Here, we show that pharmacologic inhibition of lactate dehydrogenase-A suppressed the conversion of hyperpolarized (13)C-pyruvate to
Mette Hauge Lauritzen et al.
NMR in biomedicine, 26(11), 1496-1500 (2013-06-25)
A change in myocardial metabolism is a known effect of several diseases. MRS with hyperpolarized (13)C-labelled pyruvate is a technique capable of detecting changes in myocardial pyruvate metabolism, and has proven to be useful for the evaluation of myocardial ischaemia
Ilwoo Park et al.
Journal of magnetic resonance imaging : JMRI, 33(6), 1284-1290 (2011-05-19)
To demonstrate the feasibility of using DNP hyperpolarized [1-(13)C]-pyruvate to measure early response to temozolomide (TMZ) therapy using an orthotopic human glioblastoma xenograft model. Twenty athymic rats with intracranial implantation of human glioblastoma cells were divided into two groups: one
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Global Trade Item Number

SKUGTIN
677175-1G04061826589960
677175-100MG04061833239117
677175-5G04061832748337