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679046

Sigma-Aldrich

Cholest-5-en-26,26,26,27,27,27-d6-3-ol

98 atom % D, 97% (CP)

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Synonym(s):
Cholesterol-26,26,26,27,27,27-d6
Empirical Formula (Hill Notation):
C27D6H40O
CAS Number:
60816-17-3
Molecular Weight:
392.69
MDL number:
MFCD00201281
PubChem Substance ID:
329760707

isotopic purity

98 atom % D

Assay

97% (CP)

form

solid

technique(s)

mass spectrometry (MS): suitable

bp

360 °C

mp

147-149 °C

mass shift

M+6

SMILES string

[H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])[C@H](C)CCCC(C([2H])([2H])[2H])C([2H])([2H])[2H]

InChI

1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1/i1D3,2D3

InChI key

HVYWMOMLDIMFJA-QSOBUISFSA-N

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Biyu Hou et al.
Frontiers in endocrinology, 11, 359-359 (2020-07-14)
Metabolic changes associated with diabetes are reported to lead to the onset of early-stage diabetic nephropathy (DN). Furthermore, lipotoxicity is implicated in renal dysfunction. Most studies of DN have focused on a single or limited number of lipids, and the
Fubito Nakatsu et al.
The Journal of cell biology, 199(6), 1003-1016 (2012-12-12)
Plasma membrane phosphatidylinositol (PI) 4-phosphate (PtdIns4P) has critical functions via both direct interactions and metabolic conversion to PI 4,5-bisphosphate (PtdIns(4,5)P₂) and other downstream metabolites. However, mechanisms that control this PtdIns4P pool in cells of higher eukaryotes remain elusive. PI4KIIIα, the

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