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Merck
CN

679097

(R)-(−)-2-Methylpyrrolidine

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About This Item

Empirical Formula (Hill Notation):
C5H11N
CAS Number:
Molecular Weight:
85.15
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
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refractive index

n20/D 1.4353

Quality Segment

density

0.842 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

C[C@@H]1CCCN1

InChI

1S/C5H11N/c1-5-3-2-4-6-5/h5-6H,2-4H2,1H3/t5-/m1/s1

InChI key

RGHPCLZJAFCTIK-RXMQYKEDSA-N

Application

(R)-(−)-2-Methylpyrrolidine, an optically active amine that can be used as a key building block to synthesize:
  • 4,5-fused pyridazinone derivatives are applicable as potent histamine H3 receptor antagonists.
  • Naphthalenoid histamine H3 receptor antagonist.
  • Pyrrolo[2,3-d]pyrimidine derivatives as potent inhibitors of leucine-rich repeat kinase 2.



signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Flam. Liq. 2 - Skin Corr. 1B

Storage Class

3 - Flammable liquids

flash_point_f

45.0 °F - closed cup

flash_point_c

7.22 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter



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