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Merck
CN

68571

Aminomethyl ChemMatrix® resin

0.50-0.70 mmol/g loading (amine)

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About This Item

NACRES:
NA.22
UNSPSC Code:
12352200
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product line

ChemMatrix®

form

crystals

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

particle size

100-200 mesh

capacity

0.50-0.70 mmol/g loading (amine)

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

General description

Aminomethyl ChemMatrix® resin is a polyethyleneglycol (PEG)-based resin, composed of highly cross-linked primary ether bonds, therefore the resin is chemically and mechanically stable in a broad range of solvents. It has good loading properties when compared to other PEG resins due to its availability in free-flowing powder form. This resin is also more effective than polystyrene resins in the synthesis of hydrophobic or highly structured polypeptides.

Application

Aminomethyl ChemMatrix® resin can be used as efficient support in solid-phase peptide synthesis (SPPS). It is also used as a starting material to synthesize dihydrolipoyl-supported polymer, which is used as an efficient and recyclable reducing agent for the reduction of disulfide compounds.

Legal Information

ChemMatrix is a registered trademark of Matrix Innovation, Inc.


Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Articles

ChemMatrix® is a proprietary, 100% PEG (polyethylene glycol) based resin from PCAS BioMatrix.

ChemMatrix®是PCAS BioMatrix专有的一种基于100%PEG(聚乙二醇)的树脂。


Convenient supported recyclable material based on dihydrolipoyl-residue for the reduction of disulfide derivatives
Bienvenu C, et al.
Tetrahedron Letters, 51(25), 3309-3311 (2010)
ChemMatrix for complex peptides and combinatorial chemistry.
Garcia-Ramos Y, et al.
Journal of Peptide Science, 16(12), 675-678 (2010)
Polyethyleneglycol-based resins as solid supports for the synthesis of difficult or long peptides
Beatriz G, et al.
International Journal of Peptide Research and Therapeutics, 13(1-2), 265-270 (2007)



Global Trade Item Number

SKUGTIN
68571-1G04061826680568
68571-5G04061833449103