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Merck
CN

700320

Iron oxide(II,III), magnetic nanoparticles solution

5 nm avg. part. size, 5 mg/mL in toluene

Synonym(s):

Magnetic iron oxide nanocrystals, Magnetite, Superparamagnetic iron oxide nanoparticles

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About This Item

Empirical Formula (Hill Notation):
Fe3O4
CAS Number:
Molecular Weight:
231.53
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12352302
MDL number:
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Product Name

Iron oxide(II,III), magnetic nanoparticles solution, 5 nm avg. part. size, 5 mg/mL in toluene

InChI

1S/3Fe.4O

SMILES string

O=[Fe].O=[Fe]O[Fe]=O

InChI key

SZVJSHCCFOBDDC-UHFFFAOYSA-N

form

nanoparticles
solution

concentration

5 mg/mL in toluene

magnetization

≥30 emu/g (at ambient temperature under 4500 Oe)

avg. part. size

5 nm

particle size

5 nm±1 nm (TEM; conforms)

density

0.865 g/mL at 25 °C

Quality Level

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General description

Concentration 5mg/ml includes total weight nanocrystals plus ligands.

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

39.9 °F

flash_point_c

4.4 °C

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

易制毒化学品(3类)
危险化学品
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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What method is used to determine the size of the particles in Product 700320, Iron oxide, magnetic?

    TEM used to check particle size. Light Scattering or similar methods are not utilized.

  6. How is the magnetization of Product 700320, Iron oxide, magnetic, determined?

    Per the supplier, the magnetization is determined by using a Magnetic Susceptibility Balance.

  7. What is the purpose of the oleic acid in Product 700320, Iron oxide, magnetic?

    Per the manufacturer, the oleic acid allows the iron oxide nanoparticles to be soluble in the solvent (i.e. toluene).

  8. What is the coating thickness of oleic acid on product number 700312, 700320, and 700304, Iron oxide(II,III), magnetic nanoparticles solution?

    The suppliers of the magnetic iron oxide nanoparticles in toluene have indicated that the particles are essentially coated with a monolayer of oleic acid. Since the oleic acid is a long chain hydrocarbon there can exist some folding and irregular structure on the surface.  The suppliers estimate that one should add 1-2 nm to the particle size due to the presence of the oleic acid coating. From this, 1.5 nm is the closest approximation of coating thickness as provided by our suppliers.

  9. How should a sample of the Iron oxide(II,III), magnetic nanoparticles solution in toluene be prepared for analysis by transmission electron microscopy (TEM)?

    The particle size is determined by TEM.If the solution as provided is not diluted, a superlattice of multilayer nanocrystals will form on the grid, appearing to be an aggregate. The solution can be diluted with the same solvent that it was shipped in (toluene). A solution diluted to 0.1-0.5 mg/mL should be concentrated enough to get a nice picture. One drop per grid should be sufficient. (Since the solution is provided at a concentration of 5 mg/mL, this would be a 10- to 50-fold dilution.)After applying the sample to the grid, a drying time of a minimum of 10-15 minutes is recommended.After performing several successful dilutions and getting good results, the analyst will get a feel for the correct dilution just by judging the color and darkness of the diluted sample. If you see lone isolated dots in the TEM, then your sample is too dilute. If you cannot distinguish separate particles, it is too concentrated. Good record keeping will help to zero in on the best dilution factor for the type of picture that you want.

  10. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Lu Zhang et al.
Nanoscale, 5(17), 7664-7684 (2013-07-24)
Superparamagnetic iron oxide nanoparticles (SPIONs) have shown great promise in biomedical applications. In this review, we summarize the recent advances in the design and fabrication of core-shell and hetero-structured SPIONs and further outline some exciting developments and progresses of these
Leyong Zeng et al.
Nanoscale, 5(5), 2107-2113 (2013-02-06)
Multifunctional Fe(3)O(4)-TiO(2) nanocomposites with Janus structure for magnetic resonance imaging (MRI) and potential photodynamic therapy (PDT) were synthesized, in which Fe(3)O(4) was used as a MRI contrast agent and TiO(2) as an inorganic photosensitizer for PDT. Their morphology, structure, and
Yongxing Hu et al.
Journal of the American Chemical Society, 135(6), 2213-2221 (2013-01-26)
Controlled assembly of nanoparticles into asymmetric configurations is of great interest due to their novel properties and promising applications. In this Article, we report a generic strategy for the synthesis of dimer nanoclusters and asymmetric nanoassemblies by using magnetic colloidal
Marina I Siponen et al.
Nature, 502(7473), 681-684 (2013-10-08)
Magnetotactic bacteria align along the Earth's magnetic field using an organelle called the magnetosome, a biomineralized magnetite (Fe(II)Fe(III)2O4) or greigite (Fe(II)Fe(III)2S4) crystal embedded in a lipid vesicle. Although the need for both iron(II) and iron(III) is clear, little is known
Maoquan Chu et al.
Biomaterials, 34(16), 4078-4088 (2013-03-08)
The photothermal effect of Fe3O4 magnetic nanoparticles is investigated for cancer therapy both in vitro and in vivo experiments. Heat is found to be rapidly generated by red and near-infrared (NIR) range laser irradiation of Fe3O4 nanoparticles with spherical, hexagonal and wire-like

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