Key Documents

View All Documentation

702455

1H-Indazole-5-carboxylic acid

Name: 1<I>H</I>-Indazole-5-carboxylic acid
Brand: ALDRICH

97%

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₈H₆N₂O₂

CAS Number:

61700-61-6

Molecular Weight:

162.15

NACRES:

NA.22

PubChem Substance ID:

329762377

UNSPSC Code:

12352100

MDL number:

MFCD06804570

Assay:

97%

Form:

powder

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Segment

100

assay

97%

form

powder

mp

318-322 °C

functional group

carboxylic acid

SMILES string

OC(=O)c1ccc2[nH]ncc2c1

InChI

1S/C8H6N2O2/c11-8(12)5-1-2-7-6(3-5)4-9-10-7/h1-4H,(H,9,10)(H,11,12)

InChI key

MAVGBUDLHOOROM-UHFFFAOYSA-N

Description

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

新产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A label-free impedance assay in endothelial cells differentiates the activation and desensitization properties of clinical S1P1 agonists.

Patrick Grailhe et al.

FEBS open bio, 10(10), 2010-2020 (2020-08-19)

Sphingosine-1 phosphate receptor-1 (S1P1 ) activation maintains endothelial barrier integrity, whereas S1P1 desensitization induces peripheral blood lymphopenia. The latter is exploited in the approval and/or late-stage development of receptor-desensitizing agents targeting the S1P1 receptor in multiple sclerosis, such as siponimod

Crystal structures, binding interactions, and ADME evaluation of brain penetrant N-substituted indazole-5-carboxamides as subnanomolar, selective monoamine oxidase B and dual MAO-A/B inhibitors.

Nikolay T Tzvetkov et al.

European journal of medicinal chemistry, 127, 470-492 (2017-01-21)

The pharmacological and physicochemical analysis of structurally optimized N-alkyl-substituted indazole-5-carboxamides, developed as potential drug and radioligand candidates for the treatment and diagnosis of Parkinson's disease (PD) and other neurological disorders, is reported. Recent efforts have been focused on the development

Global Trade Item Number

SKU	GTIN
702455-1G	04061832820941