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Merck
CN

705268

Biotin-(ring-6,6-d2)

≥98 atom % D, ≥97% (CP)

Synonym(s):

D-Biotin-d2-(ring-6,6-d2), Bios II-(ring-6,6-d2), Coenzyme R-(ring-6,6-d2), Vitamin B7-(ring-6,6-d2), Vitamin B8-(ring-6,6-d2), Vitamin H-(ring-6,6-d2)

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About This Item

Empirical Formula (Hill Notation):
C10D2H14N2O3S
CAS Number:
1217481-41-8
Molecular Weight:
246.32
NACRES:
NA.24
PubChem Substance ID:
329762544
UNSPSC Code:
12352106
MDL number:
MFCD11656103
Isotopic purity:
≥98 atom % D
Assay:
≥97% (CP)
Mass shift:
M+2
Form:
powder

Key Documents

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InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1/i5D2

SMILES string

[2H]C1([2H])S[C@@H](CCCCC(O)=O)[C@H]2NC(=O)N[C@@H]12

InChI key

YBJHBAHKTGYVGT-OXQHWPBHSA-N

isotopic purity

≥98 atom % D

assay

≥97% (CP)

form

powder

technique(s)

mass spectrometry (MS): suitable

color

white to off-white

mp

231-233 °C (lit.)

mass shift

M+2

shipped in

dry ice

Quality Level

200

Related Categories

General description

Biotin-(ring-6,6-d2), an isotope-labeled analog of biotin, is also known as vitamin H (vitamin B7). It is a water-soluble vitamin B essentially involved in the synthesis of fatty acids and in gluconeogenesis. Biotin is found in plants and animals and its deficiency potentially causes retardation in growth, alopecia and neurological impairment.

Application

Biotin-(ring-6,6-d2) is also known as coenzyme R-(ring-6,6-d2). This product is used as an internal analytical standard for the quantitation of biotin concentration in dietary supplements, fortified foods or within a complex biological matrix.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

美国出口管控产品
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Certificates of Analysis (COA)

Lot/Batch Number
MBBF0632
MBBF0633
MBBF0235
MBBF0023
MBBD9358

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Factitious Graves disease due to biotin immunoassay interference-a case and review of the literature
Elston MS, et al.
The Journal of clinical endocrinology and metabolism, 101(9), 3251-3255 (2016)
Agar plate method using Lactobacillus plantarum for biotin determination in serum and urine
FUKUI T, et al.
J. Nutr. Sci. Vitaminol., 40(5), 491-498 (1994)
Magnetic resonance imaging assays for dimethyl sulfoxide effect on cancer vasculature
Cyran CC, et al.
Investigative Radiology, 43(5), 298-298 (2008)

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