722332
6-Amino-7-deazapurine
97%
Synonym(s):
4-Amino-7H-pyrrolo[2,3-d]pyrimidine
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About This Item
Empirical Formula (Hill Notation):
C6H6N4
CAS Number:
Molecular Weight:
134.14
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
Assay:
97%
Form:
solid
InChI
1S/C6H6N4/c7-5-4-1-2-8-6(4)10-3-9-5/h1-3H,(H3,7,8,9,10)
SMILES string
Nc1ncnc2[nH]ccc12
InChI key
PEHVGBZKEYRQSX-UHFFFAOYSA-N
assay
97%
form
solid
mp
257-262 °C
Quality Level
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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A I Murchie et al.
The EMBO journal, 13(4), 993-1001 (1994-02-15)
Telomeres are required for eukaryotic chromosome stability. They consist of regularly repeating guanine-rich sequences, with a single-stranded 3' terminus. Such sequences have been demonstrated to have the propensity to adopt four-stranded structures based on a tetrad of guanine bases. The
N Baran et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(2), 507-511 (1991-01-15)
To study the mechanism of arrest of DNA synthesis at d(TC)n and d(GA)n sequences, single-stranded DNA molecules including d(TC)27 or d(TC)31 tracts or a d(GA)27 tract were used as templates for in vitro assays of complementary DNA synthesis performed by
Susan J Schroeder et al.
Biochemistry, 42(48), 14184-14196 (2003-12-03)
The J4/5 loop of the group I intron in the mouse-derived fungal pathogen Pneumocystis carinii is the docking site for the first step of the RNA-catalyzed self-splicing reaction and thus is a model of a potential drug target. This purine-rich
Ivana V Yang et al.
Analytical chemistry, 74(2), 347-354 (2002-01-29)
The 7-deaza analogues of guanine and adenine were incorporated into polymerase chain reaction (PCR) products by substitution of the appropriate nucleotide triphosphates into the reaction. These PCR products can be immobilized on ITO electrodes and detected by catalytic cyclic voltammetry
A Ono et al.
Nucleic acids research, 12(23), 8939-8949 (1984-12-11)
Deoxydecanucleotides having a recognition sequence of Bgl II and Sau 3AI, and their 7-deazaadenine analogs were synthesized. The decanucleotides containing 7-deazaadenine in place of adenine were partially resistant to the hydrolysis by Sau 3AI and strongly resistant to that by
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