731099
N-(3-Aminopropyl)methacrylamide hydrochloride
contains ≤1,000 ppm MEHQ as stabilizer, 98% (HPLC)
Synonym(s):
APMA
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About This Item
Empirical Formula (Hill Notation):
C7H14N2O · HCl
CAS Number:
Molecular Weight:
178.66
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
MDL number:
Quality Level
assay
98% (HPLC)
form
powder
contains
≤1,000 ppm MEHQ as stabilizer
mp
123-128 °C
storage temp.
2-8°C
SMILES string
Cl.CC(=C)C(=O)NCCCN
InChI
1S/C7H14N2O.ClH/c1-6(2)7(10)9-5-3-4-8;/h1,3-5,8H2,2H3,(H,9,10);1H
InChI key
XHIRWEVPYCTARV-UHFFFAOYSA-N
General description
N-(3-Aminopropyl)methacrylamide hydrochloride (APMA) is an aminoalkyl methacrylamide which can be synthesized by adding 1,3-diaminopropane to 1,3-diaminopropane dihydrogen chloride solution and further mixing the solution with methacrylic anhydride and hydroquinone. It has a primary amine that provides attractive features such as pH-responsiveness, affinity for anionic drugs and conjugation for variety of chemical structures.
Application
APMA can be used in the preparation of copolymers and cross-linked miscellas for gene delivery, drug delivery and diagnostics applications.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Preparation and characterization of narrow compositional distribution polyampholytes as potential biomaterials: Copolymers of N-(3-aminopropyl) methacrylamide hydrochloride (APM) and methacrylic acid (MAA)
Dubey A, et al.
Journal of Polymer Science Part A: Polymer Chemistry, 53(2), 353-365 (2015)
Polymer mediated peptide immobilization onto amino-containing N-isopropylacrylamide-styrene core-shell particles
Rossi S, et al.
Colloid and Polymer Science, 282(3), 215-222 (2004)
Gaurasundar M Conley et al.
Nature communications, 10(1), 2436-2436 (2019-06-06)
Thermosensitive microgels are widely studied hybrid systems combining properties of polymers and colloidal particles in a unique way. Due to their complex morphology, their interactions and packing, and consequentially the viscoelasticity of suspensions made from microgels, are still not fully
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 731099-1G | 04061832865553 |
| 731099-5G | 04061832865560 |