739669
25-Hydroxyvitamin D3 solution
5 μg/mL in ethanol, 98% (CP)
Synonym(s):
25-Hydroxycholecalciferol solution
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About This Item
Empirical Formula (Hill Notation):
C27H44O2
CAS Number:
Molecular Weight:
400.64
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
12352205
EC Number:
200-578-6
MDL number:
Assay:
98% (CP)
Form:
solution
Quality Level
assay
98% (CP)
form
solution
concentration
5 μg/mL in ethanol
technique(s)
mass spectrometry (MS): suitable
color
colorless
application(s)
detection
storage temp.
−20°C
SMILES string
C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C
InChI
1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
InChI key
JWUBBDSIWDLEOM-DTOXIADCSA-N
Gene Information
human ... VDR(7421)
General description
25-Hydroxyvitamin D3 (calcifediol) is a prohormone produced via hydroxylation of vitamin D3 (cholecalciferol) in the liver. It is a precursor for the synthesis of calcitriol {1,25-dihydroxyvitamin D3 or [1,25(OH)2D3]}. It is also used as a biomarker to determine the status of vitamin D in the body.
Application
This product may be used as an analytical standard.
Packaging
1 mL in ampule
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signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
Storage Class
3 - Flammable liquids
wgk
WGK 1
flash_point_f
57.2 °F
flash_point_c
14.0 °C
Regulatory Information
危险化学品
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Marina V Antunes et al.
Therapeutic drug monitoring, 37(6), 733-744 (2015-04-09)
In view of the large variability on therapeutic response and the multiple factors associated to tamoxifen (TAM) metabolic activation, this study aimed to evaluate the effect of CYP2D6 and CYP3A4 phenotypes, drug interactions, and vitamin D exposure on TAM metabolism
Fadia S AlBuhairan et al.
The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 57(3), 263-269 (2015-08-25)
With the increasing burden of noncommunicable disease, adolescence is viewed as an opportune time to prevent the onset of certain behaviors and promote healthy states. Although adolescents comprise a considerable portion of Saudi Arabia's population, they have received insufficient attention
Joseph Schwager et al.
Molecular nutrition & food research, 59(8), 1513-1523 (2015-03-27)
The impact of L-ascorbic acid (L-AA) on the chemokinesis (CK) and chemotaxis (CT) of HL-60 cells and polymorphonuclear cells (PMN) was investigated. HL-60 cells were differentiated with DMSO, retinoic acid (RA), vitamin D, or L-AA. Chemokinesis and chemotaxis of differentiated
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 739669-1ML | 04061838085221 |