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Merck
CN

746207

Maleimide-PEG8-succinimidyl ester

Synonym(s):

Maleimide PEG8 succinimidyl ester, 31-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacontanoic acid 2,5-dioxo-1-pyrrolidinyl ester, Maleimide-PEG8-NHS ester, 31-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacontanoic acid 2,5-dioxo-1-pyrrolidinyl ester, Maleimide-PEG8-NHS ester

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About This Item

Empirical Formula (Hill Notation):
C30H47N3O15
CAS Number:
Molecular Weight:
689.71
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352108
MDL number:
Form:
liquid
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form

liquid

Quality Level

reaction suitability

reaction type: Pegylations, reagent type: cross-linking reagent

functional group

NHS ester, maleimide

storage temp.

−20°C

SMILES string

O=C(N1CCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O)=O)C=CC1=O

InChI

1S/C30H47N3O15/c34-25(5-8-32-26(35)1-2-27(32)36)31-7-10-41-12-14-43-16-18-45-20-22-47-24-23-46-21-19-44-17-15-42-13-11-40-9-6-30(39)48-33-28(37)3-4-29(33)38/h1-2H,3-24H2,(H,31,34)

InChI key

MTPWCXBUZLEBDD-UHFFFAOYSA-N

Application

Heterobifunctional crosslinker with an ethylene oxide spacer for linking amine- to sulfhydryl-containing compounds or biomolecules. Maleimide functional group will react with sulfhydryls and the succinimidyl ester group will react with amines. Spacer length is 39.2 angstroms.


Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Joseph L Watson et al.
The Journal of cell biology, 220(2) (2021-01-09)
Protein micropatterning allows proteins to be precisely deposited onto a substrate of choice and is now routinely used in cell biology and in vitro reconstitution. However, drawbacks of current technology are that micropatterning efficiency can be variable between proteins and



Global Trade Item Number

SKUGTIN
746207-50MG04061833241097
746207-250MG04061833241080