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Merck
CN

747181

Poly(ethylene glycol)-block-poly(N-isopropylacrylamide)

α-methoxy, ω-dodecane, PEG Mn 2,000, PNIPAM Mn 24,000, PDI <1.2

Synonym(s):

PEG-block-PNIPAM, PEG-b-polyNIPAM, PEGylated polyNIPAM, PNIPAAm

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About This Item

Linear Formula:
CH3(OC2H4)mC6H7NO2(C6H11NO)nH
NACRES:
NA.23
UNSPSC Code:
12352100
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Quality Level

form

solid

mol wt

PEG Mn 2,000, PNIPAM Mn 24,000

PDI

<1.2

General description

Poly(ethylene glycol)-b-poly(N-isopropylacrylamide) (PEG110-b-PNIPAM44) undergoes thermoresponsive micellization in water, forming micelles of varied size, structure and distribution depending on the concentration of the block copolymer.

Application

Well-defined PEG-block-PNIPAM diblock copolymers can form thermoresponsive vesicles in water and enable controlled drug release.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Articles

Professor Mitsuhiro Ebara provides insights on several types of smart nanofiber mesh systems that have been explored for different drug delivery purposes.


Thermoresponsive micellization of poly (ethylene glycol)-b-poly (N-isopropylacrylamide) in water.
Zhang W
Macromolecules, 38(13), 5743-5747 (2005)
Temperature-Controlled Assembly and Release from Polymer Vesicles of Poly(ethylene oxide)-block-poly(N-isopropylacrylamide)
Qin S, et al.
Advanced Materials, 18, 2905?2909-2905?2909 (2006)



Global Trade Item Number

SKUGTIN
747181-500MG04061833241141