751480
Malonic acid
sublimed grade, ≥99.95% trace metals basis
Synonym(s):
Propanedioic acid
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About This Item
Linear Formula:
CH2(COOH)2
CAS Number:
Molecular Weight:
104.06
EC Number:
205-503-0
UNSPSC Code:
12352300
PubChem Substance ID:
Beilstein/REAXYS Number:
1751370
MDL number:
InChI key
OFOBLEOULBTSOW-UHFFFAOYSA-N
InChI
1S/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7)
SMILES string
OC(=O)CC(O)=O
grade
sublimed grade
assay
≥99.95% trace metals basis
form
powder
mp
132-135 °C (dec.) (lit.)
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General description
The common technique for producing malonic acid is from chloroacetic acid.Malonic acid undergoes thermal decarboxylation at temperatures of 135-137oC.2
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1
Storage Class
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
314.6 °F - closed cup
flash_point_c
157 °C - closed cup
Regulatory Information
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Organic Syntheses, 18, 50-50 (1938)
E A Haan et al.
European journal of pediatrics, 144(6), 567-570 (1986-04-01)
A second child with a more severe deficiency of malonyl CoA decarboxylase is described. He is mildly mentally retarded and presented with vomiting, a seizure, hypoglycaemia and mild metabolic acidosis during a urinary tract infection. The urine contained increased amounts
Bogdan Belgorodsky et al.
Bioconjugate chemistry, 16(5), 1058-1062 (2005-09-22)
The preparation and characterization of the stable human serum albumin (HSA)-C3 isomer of tris-malonic acid [C60]fullerene complex is reported. Other than the anti-fullerene antibody, a stable protein-fullerene complex with a native protein has never been observed. This study may provide
Matthias Bauwens et al.
PloS one, 7(6), e38428-e38428 (2012-06-22)
In vivo pH imaging has been a field of interest for molecular imaging for many years. This is especially important for determining tumor acidity, an important driving force of tumor invasion and metastasis formation, but also in the process of
Anna Shevchenko et al.
International journal of pharmaceutics, 436(1-2), 403-409 (2012-07-04)
Cocrystallization and salt formation have been shown to entail substantial promise in tailoring the physicochemical properties of drug compounds, in particular, their dissolution and hygroscopicity. In this work, we report on the preparation and comparative evaluation of a new cocrystal
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