751480
Malonic acid
sublimed grade, ≥99.95% trace metals basis
Synonym(s):
Propanedioic acid
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About This Item
Linear Formula:
CH2(COOH)2
CAS Number:
Molecular Weight:
104.06
Beilstein:
1751370
EC Number:
MDL number:
UNSPSC Code:
12352300
PubChem Substance ID:
grade
sublimed grade
Assay
≥99.95% trace metals basis
form
powder
mp
132-135 °C (dec.) (lit.)
SMILES string
OC(=O)CC(O)=O
InChI
1S/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7)
InChI key
OFOBLEOULBTSOW-UHFFFAOYSA-N
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General description
The common technique for producing malonic acid is from chloroacetic acid.Malonic acid undergoes thermal decarboxylation at temperatures of 135-137oC.2
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 1
Flash Point(F)
314.6 °F - closed cup
Flash Point(C)
157 °C - closed cup
Regulatory Information
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Organic Syntheses, 18, 50-50 (1938)
E A Haan et al.
European journal of pediatrics, 144(6), 567-570 (1986-04-01)
A second child with a more severe deficiency of malonyl CoA decarboxylase is described. He is mildly mentally retarded and presented with vomiting, a seizure, hypoglycaemia and mild metabolic acidosis during a urinary tract infection. The urine contained increased amounts
Bogdan Belgorodsky et al.
Bioconjugate chemistry, 16(5), 1058-1062 (2005-09-22)
The preparation and characterization of the stable human serum albumin (HSA)-C3 isomer of tris-malonic acid [C60]fullerene complex is reported. Other than the anti-fullerene antibody, a stable protein-fullerene complex with a native protein has never been observed. This study may provide
Adriana Wilhelm et al.
Journal of medicinal chemistry, 55(22), 9817-9830 (2012-10-31)
The protein kinase C-related kinase 2 (PRK2)-interacting fragment (PIF) pocket of phosphoinositide-dependent kinase-1 (PDK1) was proposed as a novel target site for allosteric modulators. In the present work, we describe the design, synthesis, and structure-activity relationship of a series of
Christian Bonhomme et al.
Journal of the American Chemical Society, 134(30), 12611-12628 (2012-06-29)
Strontium is an element of fundamental importance in biomedical science. Indeed, it has been demonstrated that Sr(2+) ions can promote bone growth and inhibit bone resorption. Thus, the oral administration of Sr-containing medications has been used clinically to prevent osteoporosis
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