All Photos(1)

Documents

756822

Deuterium oxide

Name: Deuterium oxide
Brand: ALDRICH

filtered, 99.8 atom % D

Sign Into View Organizational & Contract Pricing

All Photos(1)

Synonym(s):

Deuterated water, Heavy water, Water-d₂

Empirical Formula (Hill Notation):

D₂O

CAS Number:

7789-20-0

Molecular Weight:

20.03

EC Number:

232-148-9

MDL number:

MFCD00044636

PubChem Substance ID:

329766620

NACRES:

NA.12

isotopic purity

99.8 atom % D

form

liquid

technique(s)

HPLC: suitable
bio NMR: suitable
protein expression: suitable

bp

101.4 °C (lit.)

mp

3.8 °C (lit.)

density

1.107 g/mL at 25 °C

SMILES string

[2H]O[2H]

InChI

1S/H2O/h1H2/i/hD2

InChI key

XLYOFNOQVPJJNP-ZSJDYOACSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Solvents

Stable Isotopes

General description

Deuterium oxide (D₂O) is also known as heavy water. It is the deuterated form of water, as both the protons in H₂O have been replaced with a deuterium isotope.

Application

D₂O can be used as a solvent in:

High-resolution NMR (Nuclear magnetic resonance)
FTIR (Fourier-transform infrared)
Bio NMR studies
Polarized visible Raman spectroscopic studies
Protein expression

D₂O is also used to prepare deuterium-labeled compounds in various fields such as pharmaceutical, bioanalytical, biological, and environmental chemistry via H-D exchange reactions to study drug metabolism mechanisms, reaction mechanisms, and the structure of biomolecules, and residual agrochemicals in foods using suitable analytical methods.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

How to Find the Product Number

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503

Product Number

25G

Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

How to Find a Lot/Batch Number for COA

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').
For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').
For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Dihedral angles of trialanine in D2O determined by combining FTIR and polarized visible Raman spectroscopy.

R Schweitzer-Stenner et al.

Journal of the American Chemical Society, 123(39), 9628-9633 (2001-09-27)

We have measured the polarized visible Raman and FTIR spectra of trialanine and triglycine in D(2)O at acid, neutral, and alkaline pD. From the Raman spectra we obtained the isotropic and the anisotropic scattering. A self-consistent spectral analysis of the

The Structural Basis for Low Conductance in the Membrane Protein VDAC upon β-NADH Binding and Voltage Gating.

Raphael Böhm et al.

Structure (London, England : 1993), 28(2), 206-214 (2019-12-22)

The voltage-dependent anion channel (VDAC) forms the primary diffusion pore of the outer mitochondrial membrane. In its apo form, VDAC adopts an open conformation with high conductance. States of lower conductance can be induced by ligand binding or the application

Closing the gap between T-cell life span estimates from stable isotope-labeling studies in mice and humans.

Liset Westera et al.

Blood, 122(13), 2205-2212 (2013-08-16)

Quantitative knowledge of the turnover of different leukocyte populations is a key to our understanding of immune function in health and disease. Much progress has been made thanks to the introduction of stable isotope labeling, the state-of-the-art technique for in

Moderate hyperventilation during intravenous anesthesia increases net cerebral lactate efflux.

Frank Grüne et al.

Anesthesiology, 120(2), 335-342 (2013-09-07)

Hyperventilation is known to decrease cerebral blood flow (CBF) and to impair cerebral metabolism, but the threshold in patients undergoing intravenous anesthesia is unknown. The authors hypothesized that reduced CBF associated with moderate hyperventilation might impair cerebral aerobic metabolism in

Determination of steady-state protein breakdown rate in vivo by the disappearance of protein-bound tracer-labeled amino acids: a method applicable in humans.

Lars Holm et al.

American journal of physiology. Endocrinology and metabolism, 304(8), E895-E907 (2013-02-21)

A method to determine the rate of protein breakdown in individual proteins was developed and tested in rats and confirmed in humans, using administration of deuterium oxide and incorporation of the deuterium into alanine that was subsequently incorporated into body

View All Related Papers