76172
O-(2-Aminoethyl)-O′-(2-azidoethyl)pentaethylene glycol
≥90% (oligomer purity)
Synonym(s):
Azido-PEG-amine (n=6)
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About This Item
Empirical Formula (Hill Notation):
C14H30N4O6
CAS Number:
Molecular Weight:
350.41
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥90% (oligomer purity)
Form:
liquid
Quality Level
assay
≥90% (oligomer purity)
form
liquid
reaction suitability
reaction type: click chemistry, reagent type: cross-linking reagent
functional group
amine, azide
storage temp.
2-8°C
SMILES string
NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
InChI
1S/C14H30N4O6/c15-1-3-19-5-7-21-9-11-23-13-14-24-12-10-22-8-6-20-4-2-17-18-16/h1-15H2
InChI key
VCQSTKKJKNUQBI-UHFFFAOYSA-N
Application
O-(2-Aminoethyl)-O′-(2-azidoethyl)pentaethylene glycol can be used:
- As a reactant for the synthesis of thin films of azide functionalized poly(L-glutamic acid) for drug delivery.
- For the synthesis of curcumin monoazide derivatives for fabricating biologically active curcumin conjugates.
- To modify the surface of TiO2 nanoparticles to attach DNA strands for photocatalytic reduction of CO2.
- For the conjugation of poly(ethylene glycol) (PEG) with toll-like receptor 7 (TLR7) to improve its pharmaceutical properties.
O-(2-Aminoethyl)-O′-(2-azidoethyl)pentaethylene glycol has been used in the synthesis of Alexa568-azide, a fluorescent azide that can undergo click staining reaction with 5-ethynyluridine-labeled cellular RNA.
signalword
Warning
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
hcodes
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Synthesis of monofunctional curcumin derivatives, clicked curcumin dimer, and a PAMAM dendrimer curcumin conjugate for therapeutic applications.
Shi W, et al.
Organic Letters, 9(26), 5461-5464 (2007)
Low-fouling, biofunctionalized, and biodegradable click capsules.
Ochs CJ, et al.
Biomacromolecules, 9(12), 3389-3396 (2008)
Exploring RNA transcription and turnover in vivo by using click chemistry.
Jao CY & Salic A.
Proceedings of the National Academy of Sciences of the USA, 105(41), 15779-15784 (2008)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 76172-500MG-F | 04061832918525 |
| 76172 | 04065265648721 |