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763314

sSPhos Pd G2

Name: sSPhos Pd G2
Brand: ALDRICH

95%, solid

Sustainability features

Synonym(s):

Chloro(sodium-2-dicyclohexylphosphino-2′,6′-dimethoxy-1,1′-biphenyl-3′-sulfonate)[2-(2′-amino-1,1′-biphenyl)]palladium(II)

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About This Item

Empirical Formula (Hill Notation):

C₃₈H₄₄ClNNaO₅PPdS

CAS Number:

2375242-78-5

Molecular Weight:

822.66

UNSPSC Code:

12161600

PubChem Substance ID:

329767044

NACRES:

NA.22

MDL number:

MFCD22377809

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Properties

Product Name

sSPhos Pd G2, 95%

Quality Segment

100

product line

Buchwald precatalyst Generation 2

assay

95%

form

solid

feature

generation 2

reaction suitability

core: palladium, reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Heck Reaction, reaction type: Hiyama Coupling, reaction type: Negishi Coupling, reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Suzuki-Miyaura Coupling, reagent type: catalyst
reaction type: Cross Couplings

sustainability

Sustainability features

mp

193-194 °C (decomposition)

functional group

phosphine

greener alternative category

SMILES string

[Na+].Nc1ccccc1-c2ccccc2[Pd]Cl.COc3ccc(c(OC)c3-c4ccccc4P(C5CCCCC5)C6CCCCC6)S([O-])(=O)=O

InChI

1S/C26H35O5PS.C12H10N.ClH.Na.Pd/c1-30-22-17-18-24(33(27,28)29)26(31-2)25(22)21-15-9-10-16-23(21)32(19-11-5-3-6-12-19)20-13-7-4-8-14-20;13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;;;/h9-10,15-20H,3-8,11-14H2,1-2H3,(H,27,28,29);1-6,8-9H,13H2;1H;;/q;;;2*+1/p-2

InChI key

MWQYWXJKMDRSJN-UHFFFAOYSA-L

Description

General description

We are committed to providing greener alternatives that adhere to the 12 Principles of Green Chemistry. This precatalyst serves as a highly active precatalyst for cross-coupling reactions, enabling efficient C-C and C-N bond formation with reduced catalyst loading, thus aligns with Green Chemistry principle "Catalysis". Click here for more information.

Application

sSPhos Pd G2 can be used as a water-soluble Pd-precatalyst in:

DNA-compatible Suzuki-Miyaura reaction between DNA-linked aryl halides and various boronic acids/esters including heteroaryl boronates.
DNA-compatible hydroxycarbonylation reactions.
The cross-coupling reaction between boronic ester and brominated cyclic nucleotide to synthesize cyclic adenosine and guanosine monophosphate in the presence of potassium phosphate and hydrochloric acid.

Storage Class

11 - Combustible Solids

Flash Point (°F)

Not applicable

Flash Point (°C)