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Merck
CN

764604

Sigma-Aldrich

Polyethylenimine, linear

average Mn 2100, PDI <1.3

Synonym(s):

PEI

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About This Item

Linear Formula:
(CH2CH2NH)n
CAS Number:
9002-98-6
MDL number:
MFCD00039669
UNSPSC Code:
12162002
NACRES:
NA.23

Key Documents

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form

liquid

mol wt

average Mn 2100

mp

59-64 °C

transition temp

Tm 59-64 °C

PDI

<1.3

storage temp.

2-8°C

SMILES string

N1CC1

InChI

1S/C2H5N/c1-2-3-1/h3H,1-2H2

InChI key

NOWKCMXCCJGMRR-UHFFFAOYSA-N

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General description

Polyethylenimine(PEI) is a synthetic cationic polymerwith high charge density and chain flexibility. It is the most widelyinvestigated cationic polymer for non-viral delivery of nucleic acids. LinearPEI can be an effective carrier for a wide range of gene medicine including DNAplasmids, small interfering RNAs, and mRNAs. It protects the DNA from theacidic environment and ensures the release of DNA to the cytoplasm.

Application

  • Water-soluble linear poly (ethylenimine) as a superior bifunctional binder for lithium–sulfur batteries: Demonstrates the utility of water-soluble linear polyethylenimine as an effective bifunctional binder that enhances the cycle stability and efficiency of lithium-sulfur batteries, pivotal for advancing battery technology (Liao et al., 2018).

Signal Word

Danger

Hazard Statements

H302,H317,H318,H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV2167
MKCT1323
MKCT1326
MKCT1325
MKCM1906

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Lei Feng et al.
Engineering in life sciences, 20(8), 320-330 (2020-08-11)
As the main immunogen that could stimulate neutralized antibody in pigs, recombinant E2 protein of CSFV was expressed in CHO-dhfr-cells driven by endogenous Txnip promoter from Chinese hamster. Different fragments of Txnip promoter were amplified by PCR from isolated genomic
Laura R H Ip et al.
Oncotarget, 6(12), 10548-10562 (2015-04-15)
Treatment options for ovarian cancer patients remain limited and overall survival is less than 50% despite recent clinical advances. The lipid phosphatase inositol polyphosphate 4-phosphatase type II (INPP4B) has been described as a tumor suppressor in the PI3K/Akt pathway with

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Functionalized PEI and Its Role in Gene Therapy

Gene therapy has become one of the most discussed techniques in biomedical research in recent years.

Microfluidics for Nanoencapsulation of Nucleic Acids

Microfluidic assembly improves polyamine nanoencapsulation of nucleic acids, overcoming challenges like polydispersity and poor reproducibility.

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