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Merck
CN

764620

Poly(D,L-lactide)

greener alternative

average Mn 10,000, PDI ≤1.4

Synonym(s):

PDLA, PLA, polyDL-lactide

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About This Item

NACRES:
NA.23
UNSPSC Code:
12162002
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form

solid

Quality Level

optical activity

[α]/D 0°, c = 0.5% in chloroform

mol wt

average Mn 10,000

greener alternative product characteristics

Design for Energy Efficiency
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

degradation timeframe

<6 months

mp

287-293 °C

PDI

≤1.4

greener alternative category

storage temp.

2-8°C

General description

We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This is an enabling product that belongs to a family of high-performance bio-based polymers that are essential for developing efficient, low-cost, and environmentally friendly renewable energy solutions. Click here for more information.

Application

Used in Drug Delivery including coating nanoparticles1. Can be end-group functionalizated2 or used as a macroinitiator/block precursor3.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Articles

In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.

Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration.

Microparticles in drug delivery: Study on controlling chitosan microparticle size and distribution, exploring encapsulation of BSA and TPP cross-linker.

View All Articles

Zhang, Wen-Bin; et al.
Macromolecules, 44, 2589-2596 (2011)
Wolf, Florian F.; et al.
Macromolecules, 42, 5622-5628 (2009)
Preparation of Protein-Loaded Poly(L-Lactide) Microspheres by Solution-Enhanced Dispersion by Supercritical CO2
Chen A Z, et al.
Journal of Biomimetics, Biomaterials, and Tissue Engineering, 11, 93-100 (2011)



Global Trade Item Number

SKUGTIN
764620-5G04061832923093